GI

Question 1

Haemochromatosis - typical iron study profile

Answer 1

transferrin saturation > 55% in men or > 50% in women
raised ferritin (e.g. > 500 ug/l) and iron
low TIBC

Question 2

Who may be considered for HCC screening?

Answer 2

Screening with ultrasound (+/- alpha-fetoprotein) should be considered for high risk groups such as:
patients liver cirrhosis secondary to hepatitis B & C or haemochromatosis
men with liver cirrhosis secondary to alcohol

Question 3

Oesophageal Ca Adenocarcinoma RFs?

Answer 3

Lower third - near the gastroesophageal junction

GORD
Barrett’s oesophagus
smoking
obesity

Question 4

Oesophageal Ca Squamous Cell Carcinoma RFs?

Answer 4

Upper two-thirds of the oesophagus

smoking
alcohol
achalasia
Plummer-Vinson syndrome
diets rich in nitrosamines