MISC

Question 1

Normal Angion Gap Metabolic Acidosis Causes

Answer 1

Normal anion gap ( = hyperchloraemic metabolic acidosis)
- gastrointestinal bicarbonate loss:
prolonged diarrhoea: may also result in hypokalaemia
ureterosigmoidostomy
fistula
- renal tubular acidosis
- drugs: e.g. acetazolamide
- ammonium chloride injection
- Addison’s disease

Question 2

Raised Anion Gap Metabolic Acidosis

Answer 2

Raised anion gap
- lactate:
shock
sepsis
hypoxia
- ketones:
diabetic ketoacidosis
alcohol
- urate: renal failure
- acid poisoning: salicylates, methanol