GI Flashcards
(40 cards)
Name two types of peptic ulcers:
duodenal ulcers (young 30-55), feel better with feeding
gastric ulcers (old 55-65), feel worse with feeding
signs of symptoms: GNAWING epigastric pain
signs/symptoms of perforated ulcers:
severe epigastric pain
rigid boardlike abd
quiet bowel sounds
What are three causes of a perfed bowel?
peptic ulcer disease
ruptured diverticulum
appendicitis (rare)
This is tested by a urea breath test, can be present with duodenal or gastric ulcers
H. pylori
What is the step-wise approach for outpatient management of peptic ulcer disease?
- 1st line, everybody gets this: H2 blockers*
- -tidine*
- ranitidince (zantac) famotidine (pepcid)*
2nd line: PPIs
-azole
lansoprazole (prevacid) omeprazole (prilosec) esomeprazole (nexmium)
What musosal protective agent is used for traveler’s diarrhea and has direct action against H. pylori?
bismuth subsalicylate (peptobismal)
What mucosal protective agent is used for NSAID induced ulcer prophylaxis and it therefore given to patients with RA who take chronic NSAIDS?
Misopristol (cytotec)
H. pylori eradication therapy includes five possible 3 drug combinations. What three combinations use 2 abx + PPI?
AOC
MOC
MOA
A *amoxicillin+omeprazole+clarithromycin
O *Metronidazole + omeprazole + clarithromycin
M O C *Metronidazole + omeprazole + amoxicillin
O
A
H. pylori eradication therapy includes five possible 3 drug combinations. What are the two regimens that include 2 abx + 1 bismuth?
THE BMT BMTO is not as popular due to qid dosing
BMT: bismuth+metronidazole+tetracycline
BMTO: bismuth+metronidazole+tetracycline+omeprazole
If you suspect a bowel perf, what imaging would you order and what would it show?
upright or decubitus abd xray show in about 75% of cases
you would expect it to show free air under the abd
1) When the normal tissue lining the esophagus changes to tissue that resembles the lining of the intestine.
2) this is a serious complication of GERD.
3) this finding increases the risk of developing esophageal adenocarcinoma, which is a serious, potentially fatal cancer of the esophagus.
Barrett’s esophagus
What are normal platelet count?
150-400
With hepatitis A, the blood and stool are infectious during the _______ week incubation period:
2-6 week incubation period
Hep B is transmitted through:
blood
sexual activity
mother-fetus
Which two types of hepatitis have a vaccine?
A and B
Why do patients in the icteric phase have jaundice?
from unconjugated bilirubin
What is the Normal AST ALT lab values?
35-50
Your patients hepatitis serology shows Anti-HAV, IgM. What does that mean?
anti-HAV means their body has produced an antibody for hepatitis A
IgM means iMMEDIATE or Miserable, they are actively infected
so
they have active hep A infection
You patients hepatitis serology shows anti-HAV, IgG. How do you interpret that?
recovered hepatitis A
(G=Gone)
In hepatitis serology, HBeAg signifies what?
It indicates viral replication and infectivity of Hep B.
It means they can transmit hep B
If your patient’s hepatitis serology shows HBsAg, HBeAg, Anti-HBc, IgM, what does that mean?
They have active transmittable hep B
HBeAg (antigen is the bad guy) = transmittable
IgM=miserable, iMediate
Your patients hepatitis serology shows: HBsAg, Anti-HBc, anti-HBe, IgM, IgG. What is the diagnosis?
Chronic hep B
IgM and IgG
Your patients hepatitis serology shows: Anti-HBc, Anti-HBsAg.
What is the diagnosis?
recovered Hep B
anti- the body has developed antibodies
Your patients hepatitis serology shows:
anti-HCV, HCV RNA
What are the TWO possible diagnoses and how would you further differentiate the diagnosis?
acute or chronic Hep C
PCR is used to differentiate prior exposure (chronic hep C) from current viremia (acute hep C)