GI Digestion Overview Flashcards
what stimulates the release of Gastrin?
presence of peptides and amino acids in the stomach
what stimulates the release of CCK?
presence of fatty acids in the small intestine
and some peptides
what stimulates the release of GIP?
Presence of glucose, fatty acids and amino acids in the small intestine
what stimulates the release of secretin in the small intestine?
presence of acid in the duodenum
what effect does gastrin release have?
stimulates gastric acid secretion and mucosal growth
what effect does CCK release have?
inhibits gastric acid production and gastric emptying
causes gallbladder contraction and pancreatic enzyme release
what effect does GIP release have?
stimulates the release of insulin from the pancreas
inhibits gastric emptying and acid release
what effect does secretin release have?
stimulates the release of HCO3 for acid neutralisation and pancreatic enzyme secretion
inhibits gastric emptying and acid secretion
what is the primary target(s) for gastrin?
ECL cells (histamine) Parietal cells
what is the primary target(s) for CCK?
gallbladder
pancreas
stomach
what hormone targets the beta cells of the pancreas?
GIP
what hormone is responsible for acid neutralisation in the duodenum?
secretin
where is bicarbonate produced from?
brunner’s gland duct cells
what hormone is responsible for release of bicarbonate?
secretin
what hormone is responsible for the release of pancreatic lipase?
CCK
