GI tumors and polyps - STEP and Pathomoa and class Flashcards Preview

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Flashcards in GI tumors and polyps - STEP and Pathomoa and class Deck (5)
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What is the difference: Sessile vs. pedunculated polyp

• Sessile will be less of a bump with a stalk
• It's more of a bump right on the surface
• Pedunculated is more diverticular and it has a stalk
• Sessile is more tubular in architecture, while peduncular is more villous


What is the difference: Adenoma vs. Adenocarcinoma vs. carcinoma

when it has carcinoma in the name, it's invasive. Adenoma is pre-cursor to carcinoma. Adenocarcinoma is a glandular tissue tumor (look for the gland hyperplasia)


What are the three types of non-neoplastic polyps?

• Inflammatory
• Hamartomatous
○ Juvenile
○ Peutz-heghers
○ Cowden
○ Cronkhite-canada
• hyperplastic


What are inflammatory polyps?

• Often present with bleeding
• Often due to mucosal prolapse
○ Especially common in the rectum
• Cycles of injury and healing will result in inflammation, ulceration/erosion, epithelial hyperplasia and POLYP formation


What are hamartomatous polyps?

• Most are childhood or pre-pubertal in presentation
• Tumor-like over-growth
○ More tissue, but it's in the right place.
○ Colonic tissue histologically, growing in the colon, there's just too much of it
• Think Peutz-Jeghers
• Also worry about syndromic juvenile polyps often having a foci of dysplasia
• Also worry about future risk
○ GI carcinoma so increase screening schedule
○ Extra-GI manifestations
○ Genetic counseling?