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Renal 2 > Glomerular Disease > Flashcards

Glomerular Disease Flashcards

(16 cards)

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1
Q

What are the Signs of Glomerulonephritis?

A 
Hematuria
-RBC casts
-dysmorphic RBCs
Lipiduria
Proteinuria
Renal Failure
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2
Q

WHat is IgA nephropathy?

A

Asymptomatic hematuria with proteinuria
Macro hematuria associated w/ upper RT infection
Henloch Shurlein Hematuria

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3
Q

What are the features of Rapidly progressive glomerulonephritis? (Crescentic GN

A 
Renal Failure
Oliguria
Edema
HTN
Proteinuria
Hematuria
EMERGENCY
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4
Q

WHat are the causes of Rapidly progressing GN?

A

Direct IG attack
Immune complex deposition
Pauci-immune

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5
Q

WHat are the types of Pauci-immune GN?

A

Granulomatosis with polyangiitis
EGPA(Eosinophilic, churg-strauss)
Microscopic polyangiitis
No Imm Fl staining

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6
Q

WHat is Pulmonary renal syndrome?

A

Acute GN comb with pulm hemorrhage
Caused By: Anti-GBM Disease (goodpasture)
Systemic Vasculitis
Lupus

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7
Q

How does lupus renal disease manifest?

A 
Tubulointersititial nephritis 
Vascular disease
Thrombotic microangiopathy
Glomerulosclerosis
Glom Podocytopathy
Silent Lupus Nephritis
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8
Q

What is another name for nephrotic syndrome?

A

Glomerulonephritis

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9
Q

WHat are the features of Nephrotic Syndrome?

A 
Hypoalbuminemia
Edema
Hyperlipidemia
Thrombotic Disease
Massive Proteinuria (>3.5 g/24hr)
Hypoprotein/albumin (
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10
Q

WHat are the complications of Nephrotic Syndrome?

A

Thrombosis 2/2 loss of hemostasis control proteins
Infection 2/2 loss of Ig
Accel atherosclerosis from Hyperlipid
Protein malnutrition

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11
Q

WHat is seen on EM in MCD?

A

Effaced Foot processes

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12
Q

WHat is seen on EM in Membranous Glomerulopathy?

A

Spikes of subepithelial deposits

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13
Q

Which Glomerulonephropathies have been associated with Malignancy?

A 
MCD/Focal GS
-Hodgkin dis
-Lymphoma/Leukemia
-Solid Tumors
Prolif GN
-MALT lymphoma
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14
Q

WHat are the non-immunologic causes of glomerulonephropathy?

A

Diabetic GN
Systemic HTN
Glomerular HTN

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15
Q

What are the indications for percutaneous renal Biopsy?

A

Cause cannot be predicted with less invasive procedure
S and S point to Patho Dx
DDx includes diseases that have diff Tx or prognosis

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16
Q

WHat is the gold standard for diagnosing glomerular renal disease?

Study These Flashcards
A

Percutaneous Kidney Biopsy

Renal 2 (13 decks)

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