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Renal 2 > Peds Hematuria and Proteinuria > Flashcards

Peds Hematuria and Proteinuria Flashcards

1
Q

What lelvel of protein excretion defines proteinuria?

A

greater than 100mg/m2/day

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2
Q

What are the types of Proteinuria?

A

Glomerular
Tubular
Overflow

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3
Q

What is the management of Minimal Change Disease

A

Prednisone as soon as you rule out infection

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4
Q

What differentiates nephrotic from nephritic dis?

A

N-OTIC-4+ proteinuria

N-ITIC-

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5
Q

What are the secondary glomerulopathies?

A

Caused by SLE, DM
Drugs
Malignancy
Infection

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6
Q

When is a renal biopsy indicated in Itic and Otic Disease?

A 
>10yo
persistent or gross hematuria
HTN
Renal insuff
Low C3
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7
Q

What are the microscopic findings in MCNS?

A

Effacement of epithelial foot processes

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8
Q

What are the microscopic findings in FSGS?

A

Tubular atrophy

can’t differentiate from MCD on micro => start prednisone

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9
Q

What are the microscopic findings in MPGN?

A

Fluo: IgG deposits on BM

“tram track” on EM

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10
Q

What are the microscopic findings in PSGN?

A

Subepithelial Humps on EM

Granular appearance on IF

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11
Q

What are the microscopic findings in Membranous nephropathy?

A

Spike and Dome on EM

Thick glomerular BM on H and E

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12
Q

What are the common lab findings in PSGN?***

A 
Throat culture of GAS
Strep Ab Titer (ASO)
Dec C3
RBC casts
Bumpy Deposits on EM
Bloody stool/ purpuric rash
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13
Q

What are the common lab findings in MCNS?

A

Proteinuria or only ALBUMIN

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14
Q

What are the common lab findings in HSP?

A

IgA deposition in purpura (extensor surfaces)
Inc serum IgA
Normocytic Anemia

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15
Q

What are the common lab findings in IgA nephropathy?(Berger disease)

A

Recurrent Gross hematuria
increased serum IgA
EM- Mesangial cell proliferation

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16
Q

How is Glomerular hematuria diff from extraglomerular?

A

Extrarenal: Malar rash, purpura, arthralgia, headache
Localized: Dysuria, suprapubic pain, flank pain, edema, oliguria

17
Q

What are the clinical features of Alport syndrome?

A

High Frequ SN hearing loss
Anterior Lenticonus
UA- RBC casts, hematuria, protieinuria, pyuria
EM- split BM

18
Q

What are the overall treatments of Nephrotic Syndrome?

A 
Loop or Thiazide Diuretics
ACEI/ARB
Statins
VD and Ca
Low Na diet
19
Q

What is seen on dipstick that may or may not indicate Hematturia?

A 
Hemoglobinuria
Myoglobinuria
Drugs
Toxins
Food
Urate Crystals
20
Q

WHat are the lab findings in Alport syndrome?

A

UA- RBC casts, hematuria, proteinuria, pyuria

EM- Split BM

Renal 2 (13 decks)

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