Glomerular Diseases Flashcards Preview

Harrison's 19th Ed > Glomerular Diseases > Flashcards

Flashcards in Glomerular Diseases Deck (13)
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1
Q

Sustained proteinuria

A

> 1-2 g/24hrs

2
Q

Type of proteinuria in most glomerular diseases in adults

A

Nonselective

3
Q

Type of proteinuria in children with MINIMAL CHANGE disease

A

Selective, composed mainly of albumin

4
Q
Proteinuria 1-2gm/d
Hematuria with rbc cast 
Pyuria 
Hypertension
Fluid retention 
Rise in crea with dec in glomerular function
A

Nephritic syndrome

5
Q

Rapid rise in crea in nephritic syndrome

The clinical equivalent of the crescentic GN

A

RPGN

6
Q

RPGN + lung hemorrhage

A

Pulmonary - renal syndrome

7
Q
Proteinuria >3.0 g/d
Hypertension
Hypercholesterolemia
Hypoalbuminemia 
Edema/anasarca
Microscopic hematuria
A

Nephrotic syndrome

8
Q

ANCA-positive

Pauci-immune glomerulonephritis

A

Granulomatous polyangiitis
Microscopic polyangiitis
Churg-Strauss syndrome

9
Q

Tram tracking

A

Type I membranoproliferative GN

10
Q

No obvious glomerular lesion by LM negative for deposits by IF
Effacement of foot processes by Em

A

Minimal change (nil) disease

11
Q

Adequate renal biopsy sample

A

At least 10, ideally 20 glomeruli

12
Q

Descriptions of renal biopsy specimen

A

Diffuse >50% of glomeruli
Focal < 50%

Segmental
Global

13
Q

Most common Nephrotic sydrome in elderly
30% in adults
Uniform thickening of basement membrane by LM
Diffuse granular deposits of IgG and C3
Highest reported incidence of renal vein thrombosis, pulmonary embo, DVT

A

Membranous GN