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Harrison's 19th Ed > Rheuma > Flashcards

Flashcards in Rheuma Deck (3)
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1
Q

Most serious side effect of allopurinol

A
TEN 
Systemic vasculitis 
Bone marrow suppression 
Granulomatous hepatitis 
Renal failure
2
Q

IL 1B inhibitor

A

Anakinra

3
Q

Pegylated uricase

A

Pegloticase

Given 8mg IV every 2 weeks
Can dramaically lower serum uric acid in up to 50% of patients