Glomerulopathies

Question 1

What are Glomerular diseases and how are they categorized?

Answer 1

Glomerulonephritis is a spectrum of diseases affecting the glomerulus

Categorized by its presentations
If proteinuria side (nephrotic) or haematuria side (nephritic) depends on the cause

(SLE could be on either!)

Question 2

What is the pathology of nephritic

Answer 2

Nephritic syndrome is usually associated with inflammation of the glomerular capsule.

Question 3

How does nephritic syndrome present?

Answer 3

Triad cardinal signs:

Haematuria - visible or non- visible
Proteinuria - (<1g, sub-nephrotic)
Hypertension

Sometimes oliguria, pruritus, lethargy, oedematous and nausea

RPGN - Fatigu/sob/cough

Question 4

Name different types of nephritic syndrome

Answer 4

MC IgA nephropathy
Goodpasture’s Syndrome - Anti-GBM disease
Infective endocarditis
Vasculitis - wegners
Post Strep GN
SLE

Question 5

NephrItic Dx

Answer 5

Prior UTI: Post-strep GN/IgA nephropathy