Glucagon Flashcards
(7 cards)
1
Q
What is the MoA of Glucagon?
A
- Increase blood glucose concentration by activating hepatic glucose productio Converts Glycogen to Glucose
- Increase Cyclic AMP independent of beta-receptors or calcium flux resulting in a positive chronotropic and inotropic effect
2
Q
What are the contraindications of Glucagon?
A
- Known pacreatic tumours
- Known phaeochromocytoma (tumor of adrenal gland)
3
Q
What are the precautions of Glucagon?
A
- Reduced efffect in patients with adrenal insufficiency, alcohol induced hypoglycaemia, prolonged exercise, recent administration of glucagon, Chronic liver disease, ketogenic diets, and patients with frequent episodes of hypoglycaemia
- Patients should be placed laterally post administration
4
Q
What are the adverse effects of Glucagon?
A
GI: Nausea and vomiting
5
Q
how does glucagon present?
A
1mg (1IU) of glucagon WITH 1mL of water for injection
6
Q
What is the onset time of glucagon?
A
5 - 10minutes
7
Q
What is the duration action of Glucagon
A
12- 25 minutes
