TXA Flashcards
(8 cards)
1
Q
What is the MoA of TXA?
A
Antifibrinolytic - Binds to plasminogen, decreasing conversion to plasmin, and theyeby prevents fibrin degradation
2
Q
Presentation of TXA
A
1g/10mL
3
Q
What is the contraindication of TXA
A
- Injury occurred > 2hours prior to administration
4
Q
What is the precaution of TXA
A
- Rapid administration increases the risk of adverse effects
5
Q
What are the adverse effects of TXA
A
CNS: Seizures
CVS: Hypotension, Dizziness
GIT: Nausea, vomiting, diarrhoea
6
Q
How is TXA prepared for infusion
A
- Added to 100mL dextrose OR Normal Saline
7
Q
How many drops is TXA infused over?
A
10minutes ROUGHLY 3drops per second
8
Q
How is IM TXA given
A
Two 5mL injections into the lateral thigh
