Glucocorticoids

Question 1

how do glucocorticosteroids work?

Answer 1

• decrease neutrophil migration

- decrease prostaglandin and leukotriene synthesis

Question 2

hypothalmic pituitary adrenal axis inhibition

Answer 2

• when high doses are used for more than 2 weeks
• adrenal cortex stops releasing endogenous corticosteroids
• need to taper off to get back to normal levels

Question 3

Hi potency topicals

Answer 3

• amcinonide
• betamethasone cream
• desoximetasone
• fluocinonide
• halcinonide
• triamcinolone acetonide

Question 4

Very Hi potency

Answer 4

• betamethasone ointment
• clobetasol propionnate
• diflorasone diacetate
• halobetasol propionate

Question 5

ointment vs cream

Answer 5

ointment stay on skin longer

cream absorbs quickly