Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Biochemistry > Gluconeogenesis > Flashcards

Gluconeogenesis Flashcards

1
Q

3 main sources for gluconeogesis

A

Amino acids
Lactate
Glycerol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Where does glycerol go through glucogenogenesis to become glucose?

A

The liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the major organ for gluconeogenesis?

A

Liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is gluconeogenesis?

A

Synthesis of glucose from simpler precursors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How much glucose is needed by the body daily?

A

160g

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How much glucose does the brain need per day?

A

120g

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is exogenous?

A

Dietary glucose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

3 sources of blood glucose

A

Dietary intake
Glycogenolysis
Gluconeogenesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

When does gluconeogenesis kick in?

A

At the absence of dietary glucose in the blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is missing when the body goes from fasting to starvation?

A

Glycogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the only fuel for red blood cells?

A

Glucose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the primary fuel for the brain?

A

Glucose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Does the rate of glycolysis exceed the rate of oxidative metabolism?

A

Yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the main source of glucose during starvation?

A

The muscles, when you are starving you body breaks down muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which is the first molecule created in gluconeogenesis?

A

Pyruvate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What 2 reactions can glycerol be used for?

A

Glycolysis
Gluconeogenesis

17
Q

Other than the liver, where does gluconeogenesis take place?

A

Kidneys (10%)

18
Q

2 reasons why gluconeogenesis is not the mere reversal of glycolysis

A

Energetics
Reciprocal regulation

19
Q

How many irreversible steps in glycolysis must be bypassed in gluconeogenesis?

A

3

20
Q

Are gluconeogenesis and glycolysis identical pathways?

A

No

21
Q

Where is oxaloacetate formed?

A

In the mitochondria

22
Q

What is oxaloacetate reduced to?

A

Malate

23
Q

What enzymes uses NADH to reduce oxaloacetate to malate?

A

Malate dehydrogenase

24
Q

When is gluconeogenesis predominant over glycolysis?

A

If glucose is required

25
Q

When is glycolysis predominant over gluconeogenesis?

A

If ATP is required

26
Q

2 molecules that activate glycolysis and inhibits gluconeogenesis?

A

F-2,6 BP
AMP

27
Q

What molecule activates gluconeogenesis and inhibits glycolysis?

A

Citrate

28
Q

What does ATP inhibit?

A

PFK-1

29
Q

How does ATP inhibit PFK-1?

A

By binding to the allosteric site

30
Q

What does high concentrations of citrate increase?

A

The inhibitory effect of ATP

31
Q

What does high ATP slow?

A

Glycolysis

32
Q

What does high ATP speed up?

A

Gluconeogenesis

33
Q
A

Biochemistry (25 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions