Gonadal Hormones Inhibitors

Question 1

Used as contraceptive pill

Answer 1

Estrogen

Question 2

Used in dysfunction uterine bleeding

Answer 2

Estrogen

Question 3

Replacement therapy in ovarian hypofunction

Answer 3

Estrogen

Question 4

Used in treatment of atrophic vaginitis and osteoporosis

Answer 4

Estrogen

Question 5

Used in treatment of cancer prostate

Answer 5

Estrogen

Question 6

An anti estrogen

Answer 6

Clomiphene citrate (clomid)

Question 7

Blocks estrogen receptor in hypothalamus and pituitary so increase fsh and lh so stimulate ovulation

Answer 7

Clomiphene ( clomid)

Question 8

Used to stimulate ovulation in infertile women with normal pituitary function

Answer 8

Clomiphene ( clomid)

Question 9

From its adverse effects are ovarian enlargement and hot flushes

Answer 9

Clomiphene (clomid)

Question 10

Selective estrogen receptor modulators are

Answer 10

Tamoxifen
Raloxifene
Toremifene

Question 11

Estrogen antagonist in breast and agonist in uterus and bone

Answer 11

Tamoxifen

Question 12

Used in treatment of positive breast cancer and for primary prevention of breast cancer in women at high risk

Answer 12

Tamoxifen

Question 13

From its adverse increase risk of endometrial cancer
Thrombotic complications

Answer 13

Tamoxifen

Question 14

Agonist in bone but has no effect on uterus

Answer 14

Raloxifene

Question 15

Used in treatment and prevention of postmenopausal osteoporosis

Answer 15

Raloxifene

Question 16

It’s adverse effects are
Hot flashes
Thrombotic complications

Answer 16

Raloxifene

Question 17

Enzyme that catalyzes the production of estrogens from androgenic precursors within the ovary and peripheral tissues

Answer 17

Aromatase inhibitors

Question 18

New class of oral estrogen synthesis inhibitors

Answer 18

Aromatase inhibitors

Question 19

Aromatase inhibitors are

Answer 19

Anastrozole
Letrozole
Exemestane

Question 20

Are non steroidal competitive inhibitors of aromatase

Answer 20

Anastrozole and letrozole (femara)

Question 21

A steroidal irreversible aromatase inhibitors

Answer 21

Exemestane

Question 22

Used in treatment of postmenopausal women with estrogen receptor positive breast cancer who have received two to three years of Tamoxifen

Answer 22

Aromatase inhibitors

Question 23

Natural preparations of progesterone

Answer 23

Progesterone injection

Question 24

Synthetic preparations of progesterone

Answer 24

Medroxy progesterone acetate

Question 25

Used in Contraceptive pill Dysfunction uterine bleeding Dysmenorrhea and endometriosis Threatened abortion

Answer 25

Progesterone

Question 26

From its adverse effects are Headache Depression Weight gain Changes in lipido

Answer 26

Progesterone

Question 27

It is an anti progesterone

Answer 27

Mifepristone

Question 28

Competitive inhibitor of progesterone recey

Answer 28

Mifepristone

Question 29

Used with misoprostol to induce medical abortion in the first trimester

Answer 29

Mifepristone

Question 30

Natural preparations of androgens

Answer 30

Aldosterone and testosterone

Question 31

Synthetic androgens

Answer 31

Testosterone propionate

Question 32

Anabolic steroids

Answer 32

Nandrolone Stanozolol

Question 33

From its contraindications Prostatic tumors Liver diseases Children

Answer 33

Androgens

Question 34

From its adverse effects are Reduction in spermatogenesis after stopping Virilizing effects in females Precocious puberty Premature closure of epiphysis in children. Cholestatoc jaundice

Answer 34

Androgens

Question 35

From 5 alpha reductase inhibitors

Answer 35

Finasteride

Question 36

Inhibit 5 alpha reductase enzyme

Answer 36

5, apha reductase inhibitors

Question 37

Used in treatment of Benign prostatic hyperplasia Male baldness Hirsutism

Answer 37

5 alpha reductase inhibitors

Question 38

Competitive inhibitors of testosterone

Answer 38

Cyproterone and flutamide

Question 39

Competitive blocker oof both aldosterone and testosterone receptors

Answer 39

Spironolactone

Question 40

Used in treatment male hypersexuality

Answer 40

Cyproterone acetate

Question 41

Used in cancer prostate

Answer 41

Flutamide

Question 42

Testosterone receptors blockers are

Answer 42

Cyproterone acetate Flutamide

Question 43

They are competitive inhibitors of testosterone receptors

Answer 43

Cyproterone acetate Flutamide Spironolactone

Question 44

They are competitive blockers of testosterone

Answer 44

Cyproterone Flutamide

Question 45

It is a competitive blocker of both aldosterone and testosterone

Answer 45

Spironolactone

Question 46

Drugs used in hirsutism in females

Answer 46

Cyproterone acetate Spironolactone

Question 47

Used in male hypersexuality

Answer 47

Cyproterone acetate

Question 48

Used in cancer prostate

Answer 48

Flutamide