GORD Flashcards
1
Q
What is GORD?
A
Functionally incompetent lower oesophageal spinchter
Allows reflux of gastric contents
2
Q
What symptoms are GORD?
A
Restrosternal burning
3
Q
What drugs treat GORD?
A
Antacids
Antacid/ alginate combinations
Drugs inhibiting gastric acid secretion- H2 antagonist, PPIs
Drugs acting on oesophageal and gastric motility
4
Q
What is Barretts oesophagus?
A
Replacement of normal stratified squamous epithelium by columnar epithelium with goblet cells
5
Q
Who gets diagnosed with Barretts oesophagus?
A
Patients with long term GORD
6
Q
What can Barretts oesophagus cause?
A
Oesophageal adenocarcinoma
7
Q
What are antacids and alginates?
A
OTC meds
Alginates- peptac and gavsicon
Antacids- Co-magaldrox, Magnesium trisilicate
