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Microbiology > Gram negative cocci > Flashcards

Gram negative cocci Flashcards

1
Q

Neisseria metabolism

A

Glucose

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2
Q

Is Neisseria oxidase positive

A

Yes

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3
Q

Host defense mechanism against Neisseria

A

Membrane attack complex

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4
Q

Virulence factors of Neisseria

A

Pilli
IgA protease (inactivate IgA)
LOS (proinflammatory)
Opa proteins

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5
Q

Opa proteins

A

Mediate tight interactions with host cells

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6
Q

Neisseria meningitidis fermentation

A

Glucose and maltose

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7
Q

Neisseria meningitidis vaccines

A

Available for all types of Neisseria meningitidis

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8
Q

LOS (lipooligosaccharide)

A

Potent stimulator of the immune system

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9
Q

Neisseria meningitidis outbreaks

A

Close quarters (military camps and college dorms)

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10
Q

Neisseria meningitidis pathogenesis

A
  1. Make way to nasopharynx
  2. Travel to bloodstream
  3. LOS causes an inflammatory response
  4. Vascular injury
  5. Causes hypovolemia and shock
  6. Vasocontraction and thrombocytopenia (petechial rash)
  7. Crazy imbalance of clotting and bleeding (DIC)
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11
Q

Neisseria meningitidis causes

A

Protein C dysfunction

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12
Q

Waterhouse Frerichsen syndrome

A

Pressure in adrenals goes way up
Adrenal insufficiency

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13
Q

Neisseria meningitidis immune complex sequelae

A

Pericarditis
Arthritis

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14
Q

Signs and symptoms of Neisseria meningitidis

A

Fever
Malaise
Muscle aches (very intense)
Sore throat
Petechial rash

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15
Q

LP of Neisseria meningitidis

A

High protein
Low glucose
High white cells
Gram negative diplococci

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16
Q

Neisseria meningitidis diagnosis

A

Lab workup of CSF

17
Q

Neisseria meningitidis treatment

A

3rd gen cephalosporin
Penicillin

18
Q

Neisseria meningitidis close contact

A

Rifampin for post exposure prophalaxis

19
Q

Quadrivalent vaccine

A

Protects against 4 strains of Neisseria meningitidis

20
Q

Is neisseria gonorrhoeae encapsulated?

A

NO

21
Q

Neisseria gonorrhoeae common disease

A

STIs

22
Q

Clinical features of Neisseria gonorrhoeae

A

Inflammation of the genitalia

23
Q

Fitz-Hugh-Curtis syndrome

A

Inflammation of the peritoneum

24
Q

Triad of symptoms of Neisseria gonorrhoeae

A

Polyarthralgia
Tenosynovitis
Dermatitis

25
Q

Diagnosis of Neisseria gonorrhoeae

A

Nucleic acid amplification testing

26
Q

Treatment of Neisseria gonorrhoeae

A

Single intramuscular does of ceftriaxone
Doxycycline or macrolide

27
Q

What is Neisseria gonorrhoeae usually coinfected with

A

Chlamidya

Microbiology (5 decks)

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