Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

P2: Bacteriology > Gram Positive Bacilli Aerobes > Flashcards

Gram Positive Bacilli Aerobes Flashcards

(86 cards)

Start Studying
1
Q

Spore – forming

A

Bacillus spp.
Clostridium spp.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Non – sporeforming

A

Corynebacterium spp.
Listeria spp.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Most members are saprophytic organisms prevalent in soil, water, and air and on vegetation.

A

Bacillus spp.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Bacillus spp. Are motile except

A

B. anthracis and B. mycoides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Biochemical tests of bacillus spp.

A

(+) catalase; ferments glucose; starch hydrolyzers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

causative agent of ANTHRAX

A

Bacillus anthracis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

a disease of wild and domestic animals including sheep, goats,
horses and cattle.

A

ANTHRAX

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

produces endospores (central/subterminal) which are highly
resistant to heat and desiccation.

A

Bacillus anthracis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Habitat of Bacillus anthracis

A

SOIL (contracted by HERBIVORES)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Mode of Transmission: Inoculated with the spores, either by traumatic introduction, ingestion or inhalation during exposure to contaminated animal products.

A

Bacillus anthracis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Bacillus anthracis Gram positive (+) in chains;

A

“bamboo – fishing rod appearance”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Capsule of Bacillus anthracis

A

polypeptide D-glutamic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Bacillus anthracis Gram positive arranged singly;

A

“boxcar”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Gray to white colonies, raised with curled, irregular whirling margin

A

Bacillus anthracis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

“MEDUSA HEAD” or “ground glass colonies”

A

Bacillus anthracis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Used for Cultural Characteristics of Bacillus anthracis

A

Blood Agar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

disturbed portion of colony stands up like “BEATEN EGG WHITE” when lifted up

A

Bacillus anthracis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Gelatin: inverted pine – tree growth

A

Bacillus anthraci

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Reduced nitrates to nitrite

A

Bacillus anthracis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Pathogenicity of Bacillus anthracis

A

Polypeptide capsule
Anthrax toxin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

B. anthracis

complex protein toxin produced in vivo responsible for the signs and symptoms of disease

A

Anthrax toxin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

3 types of Anthrax toxin

A

Protective antigen (PA);
Edema factor (EF);
Lethal factor (LF)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Binds to specific cell receptors; forms a membrane channel that mediates entry of EF and LF into the cell

A

PROTECTIVE ANTIGEN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

an adenylate cyclase; with PA, it forms a toxin known as edema toxin

A

EDEMA FACTOR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
with PA forms lethal toxin which is major virulence factor and cause of death in infected animal.
LETHAL FACTOR
26
Pathology of Bacillus anthracis
CUTANEOUS ANTHRAX (Malignant Pustule) PULMONARY ANTHRAX/WOOLSORTER’S DSS. GASTROINTESTINAL ANTHRAX/MILZBRAND
27
Occurs on exposed surfaces of the arms or hands followed in frequency by the face and neck
CUTANEOUS ANTHRAX (Malignant Pustule)
28
A pruritic papule develops 1–7 days after entry of the organisms or spores through a scratch; it rapidly changes into a vesicle or small ring of vesicles, and necrotic ulcer develops
CUTANEOUS ANTHRAX (Malignant Pustule)
29
Lesions are 1 – 3 cm in diameter and have a characteristic central black eschar.
CUTANEOUS ANTHRAX (Malignant Pustule)
30
Lesions are 1 – 3 cm in diameter and have a characteristic central black eschar.
CUTANEOUS ANTHRAX (Malignant Pustule)
31
PULMONARY ANTHRAX/WOOLSORTER’S DSS.
32
Early manifestations: marked hemorrhagic necrosis and edema of mediastinum; substernal pain is prominent
PULMONARY ANTHRAX/WOOLSORTER’S DSS.
33
Hemorrhagic pleural effusion follows; cough is secondary to the effects on trachea; sepsis occur; bowel ulceration; hemorrhagic meningitis
PULMONARY ANTHRAX/WOOLSORTER’S DSS.
34
acquired through ingestion of spores and affects either the oropharyngeal or the abdominal area.
GASTROINTESTINAL ANTHRAX/MILZBRAND
35
o oropharyngealsymptomsincludesorethroat, lymphadenopathy and edema of throat and chest. o Abdominal symptoms include abdominal pain, vomiting and bloody diarrhea are clinical signs.
GASTROINTESTINAL ANTHRAX/MILZBRAND
36
In gram staining B. anthracis, the bacteriologic smear could be
Exudate, pus, sputum or blood
37
Serological tests for Bacillus anthracis
ASCOLI test ELISA Microhemagglutination
38
Fried rice Bacillus
Bacillus cereus
39
a very close relative to Bacillus anthracis, found within the soil.
Bacillus cereus
40
spores are NOT killed by BOILING
Bacillus cereus
41
Habitat: vegetative cells and spores ubiquitous in nature, may transiently colonize skin or GIT or respiratory
Bacillus cereus
42
Small shiny, compact to large, feathery, spreading type, maybe “MEDUSA head”, frosted glass colonies
Bacillus cereus
43
Penicillin resistant, beta – hemolytic, MOTILE, produces a wide zone of lecithinase on egg yolk agar
Bacillus cereus
44
Virulence Factors of Bacillus cereus
Enterotoxins (ST and LT) Cerelysin Phospolipase C Pyogenic Toxin
45
common LABORATORY CONTAMINANTS
Bacillus subtilis
46
Hay fever
Bacillus subtilis
47
used for antibiotic production
Bacillus subtilis
48
Treatment of infection with Bacillus subtilis
β – lactam antibiotics
49
Diagnostic tests for B. subtilis
i. Ascoli Test (Precipitin Test) ii. Catalase Test iii. Direct Fluorescent Antibody Test
50
differentiates Bacillus from Clostridium
Catalase test
51
Corynebacterium diphtheriae Group
C. diphtheriae C. ulcerans C. pseudotuberculosis
52
clubbed or irregularly shaped
Corynebacterium spp.
53
"coryneform or diphtheroid “ bacteria
Corynebacterium spp.
54
“Kleb-loeffler’s bacillus”
Corynebacterium diphtheriae
55
Habitat: human nasopharynx but only in carrier state
Corynebacterium diphtheriae
56
pleomorphic, club-shaped “picket-fence” or “Chinese characters”
Corynebacterium diphtheriae
57
Corynebacterium diphtheriae CULTURE and ISOLATION: Gray black after 48 hrs. May be both large and small and flat or convex
Cystine–Tellurite agar
58
Corynebacterium diphtheriae CULTURE and ISOLATION: Dark brown to black with brown to black halos
Tinsdale’s agar
59
Corynebacterium diphtheriae CULTURE and ISOLATION: Pleomorphic appearance, arranged side by side Display metachromatic granules – “ Babes-Ernst granules”
Loeffler agar
60
Corynebacterium diphtheriae virulence factor:
DIPTHERIA TOXIN
61
Corynebacterium diphtheriae virulence factor:
DIPTHERIA TOXIN
62
a potent exotoxin that destroys host cells by inhibiting protein synthesis
DIPTHERIA TOXIN
63
Pathology/Spectrum of Dss of Corynebacterium diphtheriae
RESPIRATORY DIPTHERIA CUTANEOUS DIPHTHERIA
64
a pharyngitis characterized by the development of an exudative membrane that covers the tonsils and pharyngeal wall.
RESPIRATORY DIPTHERIA
65
• Barcoo rot • Slow healing ulcers and membrane formation • Complication is less common
CUTANEOUS DIPHTHERIA
66
an animal pathogen causing mastitis in domestic animals
Corynebacterium ulcerans
67
MOT: contact with animals and/or ingestion of unpasteurized dairy products
Corynebacterium ulcerans
68
MOT: contact with animals and/or ingestion of unpasteurized dairy products
Corynebacterium ulcerans
69
an animal pathogen causing granulomatous lymphadenitis in humans
Corynebacterium pseudotuberculosis
70
Virulence factor of Corynebacterium pseudotuberculosis
dermonecrotic toxin; can also produce diphtheria toxin
71
MOT of Corynebacterium pseudotuberculosis
contact with animals
72
Motile with the characteristic of tumbling motility
Listeria monocytogenes
73
Gram positive coccobacilli, in singly or short chains resembling streptococci
Listeria monocytogenes
74
Culture: small, smooth, translucent grayish blue colonies surrounded by a narrow zone of beta hemolysis
Listeria monocytogenes
75
SIM: umbrella-shaped / inverted Christmas tree at 25°C but not at 35°C
Listeria monocytogenes
76
VF of Listeria monocytogenes
Flagella Endotoxin –Listeriolysin O (hemolytic & cytotoxic)
77
Pathology of Listeria monocytogenes
1. Granulomatosisinfantiseptica 2. Neonatalmeningitis 3. Septicemia
78
Specimens for diagnosis of listeriosis
blood, swabs of lesions and CSF
79
Specimens for diagnosis of listeriosis
blood, swabs of lesions and CSF
80
“red disease”
Erysipelothrix rhusiopathiae
81
“red disease”
Erysipelothrix rhusiopathiae
82
Only species in the genus that cause human disease; not part of the human flora
83
Only species in the genus that cause human disease; not part of the human flora
84
Erysipelothrix rhusiopathiae
85
Gelatin stab culture – “pipe cleaner” or “test tube brush” pattern at 22 deg. Celsius
Erysipelothrix rhusiopathiae
86
localized skin infection that resembles streptococcal erysipelas; self- limiting
Erysipeloid

P2: Bacteriology (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions