Gram Positive Cocci Flashcards

(50 cards)

1
Q

Catalase positive, coagulase positive

A

Staph aureus

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2
Q

Catalase positive, coagulase negative, novobiocin sensitive

A

Staph epidermidis

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3
Q

Catalase positive, coagulase negative, novobiocin resistant

A

Staph saprophyticus

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4
Q

Halotolerant on mannitol salt agar

A

Staph aureus

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5
Q

Pigment responsible for gold color of Staph aureus

A

Staphyloxanthin

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6
Q

Virulence factor of Staph aureus that destroys neutrophils and macrophages

A

Panton-Valentine (PV) Leukocidin

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7
Q

Tissue penetrance virulence factors

A

Hyaluronidase, collagenase, lipase, fibrinolysin

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8
Q

Causes epidermal separation in SSSS by cleaving desmoglein in desmosomes

A

Exfoliatin

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9
Q

Causes Staph aureus toxic shock syndrome

A

TSST-1

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10
Q

Characteristics of Staph aureus endocarditis (3)

A
  1. Most common cause of acute endocarditis; 2. Tricuspid valve; 3. IV drug users
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11
Q

Sequestered osteomyelitis in the metaphysis of long bones

A

Brodie abscess

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12
Q

Level of epidermal separation in SSSS

A

stratum granulosum

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13
Q

Level of epidermal separation in SJS/TEN

A

Dermoepidermal junction

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14
Q

Strawberry tongue, desquamating rash, multiorgan involvement; no site of pyogenic inflammation, culture negative

A

Staph Toxic shock syndrome

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15
Q

Side effect of vancomycin if given as a bolus

A

Red Man syndrome

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16
Q

Treatment options for staph aureus (3)

A
  1. Oxacillin, nafcillin, dicloxacillin; 2. Vancomycin if MRSA; 3. Linezolid if vancomycin-resistant
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17
Q

Criteria for food poisoning (2)

A
  1. At least 2 people with the same symptoms; 2. Causative organism has been identified
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18
Q

Possesses a glycocalyx; forms a biofilm that adheres most especially to prostheses

A

Staph epidermidis

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19
Q

2nd most common cause of UTI in sexually active women

A

Staph saprophyticus

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20
Q

Treatment for staph saprophyticus

A

TMP-SMX, quinolones

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21
Q

Catalase negative, alpha hemolytic, bile and optochin sensitive; “lancet” shaped diplococci

A

Strep pneumoniae

22
Q

Catalase negative, alpha hemolytic, bile and optochin resistant

A

Viridans strep

23
Q

Catalase negative, beta hemolytic, bacitracin sensitive

A

Strep pyogenes (Group A)

24
Q

Catalase negative, beta hemolytic, bacitracin resistant

A

Strep agalactiae (Group B)

25
Catalase negative, gamma hemolytic
Group D strep (enterococci)
26
Positive PYR test
Strep pyogenes, Group D strep
27
Virulence enzyme in Strep pyogenes that activates plasminogen; used as thrombolytic therapy in MI
Streptokinase (fibrinolysin)
28
Spreading factor
Hyaluronidase
29
Strep pyogenes toxin that produces scarlet fever
Erythrogenic toxin
30
Documents antecedent strep pharyngitis
Streptolysin O (ASO)
31
Strep pyogenes toxin that causes strep toxic shock syndrome
Pyogenic exotoxin A
32
Strep pyogenes toxin that causes necrotizing fasciitis
Exotoxin B
33
Documents antecedent strep pyoderma/impetigo
Anti-DNAse B
34
Impetigo contagiosa
Strep pyogenes
35
Impetigo bullosa
Staph aureus
36
multiorgan involvement; with recognizable site of pyogenic inflammation, culture positive
Strep toxic shock syndrome
37
Molecular mimicry with this antigen incites immune response against joints (rheumatic fever), heart (RHD), kidneys, and brain tissue
M antigen (strep pyogenes)
38
Hypersensitivity reaction of rheumatic fever/RHD
Type II
39
Hypersensitivity reaction of PSGN
Type III
40
Growth medium for Strep agalactiae
LIM broth
41
UTI in pregnant women; most common cause of neonatal sepsis, pneumonia and meningitis
GBS (Strep agalactiae)
42
Chemoprophylaxis for GBS (+) pregnant women
IV penicillin or ampicillin 4 hours prior to delivery
43
Tx for strep agalactiae
Pen G +/- aminoglycoside
44
Growth medium for Group D strep
Bile-esculin agar
45
Halotolerant Group D strep
Enterococcus faecalis
46
Strep bovis heart infection in patients with abdominal malignancy
Marantic endocarditis
47
Positive quellung reaction
Strep pneumoniae
48
Most common cause of CAP, bacterial meningitis in the elderly, septic shock in the asplenic
Strep pneumoniae
49
Most common cause of subacute and native valve endocarditis
Strep sanguis (Viridans strep)
50
Dental caries
Strep mutans (Viridans strep)