Gross pathology of cattle- endocrine and hematopoietic system

Question 1

Gross lesions in calf with congenital hypothyroidism

Answer 1

1. Lack of hair
2. Severe edema, myxedema
3. Ventral cervical swelling (hyperplastic goiter)

Question 2

Gross lesions in cow with hypothyroid calf

Answer 2

Prolonged gestation
Retained placenta
Dystocia

Question 3

Three causes of congenital hypothyroidism

Answer 3

1. Decreased maternal iodine
2. Increased material iodine
3. Genetic enzyme defect

Question 4

Unusual presentation of lymphoma

Answer 4

Bone marrow infiltration leading to hemorrhages on epicardium (or elsewhere)

Question 5

Two causes of granulomatous lymphadenitis

Answer 5

1. Myobacterium (TB)
2. Hairy vetch toxicity (lectins induce type IV hypersensitivity)

Question 6

Pigmented lymph node in a cow

Answer 6

Infection with Fascioloides magna

Question 7

Cause of icterus and enlarged spleen

Answer 7

Anaplasma marginale

Question 8

Cause of icterus and large spleen WITH hemoglobinuria

Answer 8

Babesia bovis

Question 9

What toxin causes hemorrhage with acute exposure, and is carcinogenic with chronic exposure?

Answer 9

Bracken fern- ptaquiloside

Question 10

What toxin causes insidious hemorrhagic disease with massive hemorrhage into cavities?

Answer 10

Coumarins (dicumarol) from moldy sweet clover or hay