Growth Factors Flashcards
1
Q
what stimulates vascular remodeling, fibroblast growth and production of Type 1 and III collagen
A
PDGF
2
Q
what is secreted by platelets and macrophages
A
PDGF
3
Q
what stimulates angiogenesis, fibrosis, and inhibits proliferation of other cells
A
TGF-B
4
Q
what is released initially from platelets but then followed by leukocytes, macrophages, fibroblasts, and keratinocytes
A
TGF-B
5
Q
what uses SMAD signaling
A
TGF-B
6
Q
what FGF stimulates angiogenesis and fibroblast activity
A
FGF1/2
7
Q
what FGF stimulates cell proliferation
A
FGF7
8
Q
what stimulates angiogenesis in wound healing, developing embryo, and collateral circulation
A
VEGF
9
Q
what stimulates cel proliferation via tyrosine kinase activity
A
EGF
10
Q
what is implicated in cancers
A
EGF
