Guest Lecture Flashcards

1
Q

what are barriers to effective pain management concerning the physician?

A
  • Believing patients always tell when having pain
  • Lack of training/knowledge
  • Fear of regulatory scrutiny
  • Concerns about addiction and side effects
  • Time consuming
  • Pain management is secondary to disease management
  • Believing pain is a symptom, not a disease
  • Failure to define goals and expectations
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2
Q

what are barriers to effective pain management concerning the patient?

A
  • Misconception that pain is normal
  • Unwillingness to report pain
  • Fear of side effects and addiction
  • Believing that therapy may prevent control of more severe pain in the future
  • Cognitive impairment, depression
  • Passive coping strategies
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3
Q

what are barriers to effective pain management concerning the system?

A
  • Failure to recognize/admit the magnitude of the problem
  • Lack of resources
  • Wrongful use of existing resources
  • Lack of education
  • Permissive compensatory system
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4
Q

what are the major CNCP categories?

A
  • Primary pain (fibromyalgia)
  • Post-traumatic pain
  • Post-surgical pain
  • Headache
  • Orofacial pain
  • Musculoskeletal pain
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5
Q

explain palliative therapy

A

The traditional approach to CNCP
- Pharmacotherapy
- Invasive interventions
- Behavioral therapy
- Hands on therapy
- Complementary & alternative medecine

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6
Q

explain effectiveness of duloxetine

A

anti-depressant
- study: -3 to 0 change
- Placebo went down 2 notches, which is clinically significant
- Difference is 0.8 notches between placebo and meds, which is not clinically significant

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7
Q

explain effectiveness of pregabalin for fibromyalgia

A

placebo works similarly, so not very significant

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8
Q

Analgesic selection should be based on pain characteristics:

A

Onset
Provocation/palliation
Quality
Region and radiation
Severity
Time

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9
Q

what are invasive methods?

A
  • trigger point injections
  • nerve blocks
  • spinal axis interventions

super invasive:
- Peripheral nerve, spinal cord & brain stimulation
- Implanted spinal pump

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10
Q

what are the outcomes of invasive treatments?

A
  • Not enough scientific evidence justifying nerve block therapy for chronic LBP1
  • Most high quality studies show minimal long-term effect to spine interventions
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11
Q

what is Complementary & alternative medicine?

A
  • Treatment approaches that fall outside the realm of conventional medicine
  • Practices neither taught widely in medical schools nor generally available in hospitals
  • Underutilized due to lack of scientific evidence/funding
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12
Q

what are the outcomes of palliative therapeutic for CNCP?

A

4-year community study1:
- Increased prevalence (45.5 to 53.8%)
- 79% still reported pain after 4 years
Retrospective study of patients with CRPS2:
- None had recovered
- In most- only modest symptom improvement
- Improvement not necessarily associated with therapy

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13
Q

The death rate from cancer in the U.S., adjusted for population size and age, dropped by only ___ from 1950 to 2005

A

5%
- While palliation is effective for certain cancers, it ranks far behind both early detection and risk-factor modification in its potential to reduce cancer mortality

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14
Q

what are the Similarities between cancer and chronic pain?

A
  • High prevalence
  • Multi-factorial etiologies
  • Multitude of palliative therapeutic approaches
  • Although frequently beneficial most current approaches have, so far, failed to change outcome
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15
Q

what were the results of Immunization against CNCP?

A

Early vaccination resulted in:
- Reduced incidence of HZ by 51.3%
- Reduced burden of illness by 61.1%
- Reduced incidence of PHN by 66.5%

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16
Q

what were the results of Following fMRI-guided training?

A
  • Humans could learn how to control activation of rostral anterior cingulate cortex1
  • In chronic pain patients: one day training resulted in a significant pain reduction (64% MPQ, 44% VAS)
17
Q

how should we approach the future of preventing CNCP?

A

identify environmental factors + phenotype and genotype patients at risk –> explore preventative analgesia –> prevention of CNCP