Guide For The Care & Use Of Laboratory Animals Flashcards
Which statement describes the concept of refinement?
A- strategies that result in the same scientific outcomes with using fewer animals per experiment
B- using non-animal methods of obtaining scientific data
C- strategies that result in procedures that enhance anima wellbeing and minimize pain and distress
D- using invertebrate animas instead of vertebrate animals in research
C- strategies that result in procedures that enhance animal wellbeing and minimize pain and distress
What is an engineering standard?
A guideline that specifies in detai a method or technique for achieving a desired outcome
How does the Guide describe a Policy?
A practical statement of collective wisdom
Which of the following describes the Guide’s definition of “should”?
A- an action that is considered mandatory
B- a suggestion to be considered
C- a strong recommendation
D- a general guideline
C- a strong recommendation
According to the Guide, which member is NOT required on the IACUC? A- veterinarian B- committee chair C- scientist D- a general guideline
B- committee chair
Which of these tasks is a function of the IACUC?
A- submitting inspection reports to the facility veterinarian
B- conducting the animal census
C- inspecting animal facilities
D- determining per diem rates
C- inspecting animal facilities
The IACUC should meet at least how often?
As often as necessary to fulfill its obligations
What does the acronym IACUC stand for?
Institutional Animal Care and Use Committee
Which topic should be considered in the preparation and review of an animal care and use protocol?
A- unnecessary duplication of experiments and method of euthanasia
B- the animal vendor used and delivery method
C- current animal census and per diem rates
D- animal technician scheduling
A- unnecessary duplication of experiments and method of euthanasia
Which statement is an important guideline when using physical restraints?
A- restraint devices are not to be considered normal methods of housing
B- animals must be able to eat and drink while being restrained
C- restraint must not exceed 12 hours under any circumstances
D- veterinary staff must be present while the animal is being restrained
A- restraint devices are not to be considered normal methods of housing
Which statement about major survival surgery is NOT true?
A- major survival surgery includes any procedure conducted under anesthesia
B- whether a procedure is considered “major” may be decided by the IACUC and veterinarian, for non-USDA covered species
C- major survival surgery may include laparoscopic surgery
D- major survival surgery includes any surgical procedure that produces substantial pain
A- major survival surgery includes any procedure conducted under anesthesia
Which statement is a valid justification for allowing multiple major survival surgeries?
A- the surgeries are related components of a esearch project
B- it wil save the investigators time
C- the animals used are very expensive
D- the investigator wants to reuse the animal on a new protocol
A- the surgeries are related components of a research project
If an animal of a species covered by the Animal Welfare Act has undergone one major survival surgery, and an investigator requests to use the animal on a different protocol which includes another major survival surgery, what agency must approve this?
USDA
Animals on a fluid regulation protocol should have their body weights recorded at least how often?
Once a week
Who is responsible for providing formal or on-the-job training to personnel for animals?
The institution
True or False
Non-degree training, such as certification programs for laboratory animal technicians and technologists, is an accepted means for obtaining qualifications for working with laboratory animals.
True
The extent and level of participation of personnel in the occupational health and safety program depends on all of the following except: A- the hazards posed by the animals B- exposure intensity C- susceptibility of personnel D- personnel employment status
D- personnel employment status
All of the following are important parts of an occupational health program EXCEPT:
A- pre-employment healthy evaluation
B- appropriate immunization schedule
C- collection and storage of blood serum samples for all employees
D- early diagnosis of allergies
C- collection and storage of blood serum samples for all employees
All of the following are recommended for personnel working with nonhuman primates, EXCEPT:
A- access to antibiotic drugs
B- access to a bite and scratch kit
C- instruction in the proper use of a bite kit
D- tuberculosis screening
A- access to antibiotic drugs
When conducting scientific research using hazardous biological agents, what publication should be consulted and followed?
Biosafety in Microbiological and Biomedical Laboratories
Who should be involved in determining the humane endpoints in a study?
IACUC, the veterinarian, and the PI
When is it permissible to use non-pharmaceutical grade substances on animals?
When permission is granted from the IACUC
Whic of the following should NOT be included in the facility’s disaster plan?
A- how the facility will protect irreplaceable animals
B- how the facility will prevent animal pain and distress if the HVAC system fails
C- how the facility will provide animals with potable water in the case of a disaster
D- how the facility will prevent the use of expired anesthetic and analgesics on animals
D- how the facility will prevent the use of expired anesthetic and analgesics on animals
The majority of poikilothermic laboratory animals are:
Fish and aquatic amphibians
