Gustation and Olfaction Flashcards
(21 cards)
What are the 6 tastes?
Salt, sweet, fat, umami, sour, bitter
______ are taste sensitive structures
papillae
Basolateral surface is outside/inside of the taste buds, andd its where communication to NS happens
inside
How many types of taste cells in a single taste bud?
3
Salts detect sodium ions, causing taste cells to depolarise through which channels?
amiloride sensitive Na channels
Sensory transduction of sour tastes involves intracellular acidification, leading to a block in which channels?
potassium channels in membranes
T/F- Voltage gated channels respond to salty tastes
False- they dont
Sensory transduction of sweet and umami tastes include heterodimer G protein receptors. Sweet taste contains \_\_\_\_\_\_ receptors whereas umami receptors contain \_\_\_\_\_\_\_ receptors. A) T1R2/T1R3, T1R1/T1R3 B) T1R2/T1R1, T1R1/T1R3 C) T1R2/T1R3, T1R2/T1R3 D) T1R2/T1R1, T1R1/T1R2
A) T1R2/T1R3, T1R1/T1R3
In sensory transduction of sweet and umami tastes, receptors couple to phospholipase C modulate _____, leading to release of _____.
A) Na, K
B) K, na
C) K, Ca
D) Na, Ca
C) K,Ca
T1R1/T1R3 receptors respond to _____, and are enhanced by _____.
A) glutamate, inosine
B) GABA, inosine
C) glutamate, diosine
D) GABA, diosine
A)
Depolarisation of taste cells leads to the release of excitatory transmitters that depolarise gustatory afferent terminals. ATP is one of those. What does it do?
activates ionotropic receptors on terminal membrane of gustatory axons
Gustatory afferents synapse at ______, part of the _____. It then projects to _______
gustatory nucleus, solitary nuclues of medulla, ventral posterior medial nuclueus of thalamus
Olfactory epithelium is located where?
Roof of nasal cavity
Olfactory receptors cells sends axons through ____ to the ______
Cribiform plate, olfactory bulb
T/F- Each olfactory receptor cell expresses a different receptor protein,
Trueq
Describe the process of olfactory transduction
Odorant molecule–> odorant receptor molecule–> activates adenyl cyclase–> in conjuction with ATP, activates cAMP—> influx of Ca and Na–> Ca pushes Cl out–> membrane depolarisation
What is the order of the structure of the olfactory bulb?
Olfactory receptor cells-> axons of olfactory receptor cell-> Glomerulus-> Peri glomerular cells–> Tuftel cell–> Mitral cell–> then to olfactory cortex
T/F- Receptor cells that synapse on a particular glomerulus all have different receptor fields
false- express same receptor field
T/F- Indiivdual glomeruli encode only one odour, and granule cell neuron act as tuning interneuron.
True
Briefly describe the central olfactory pathway
Olfactory receptor–> (via olfactory nerve) Olfactory bulb–> (via olfactory tract) olfactory targetsr
T/F- olfactory receptor cells goes through cortex first and then the thalamus
True
