gynae intro Flashcards

(36 cards)

1
Q

what are the 2 types of looking at menstrual cycle

A

ovarian
uterine

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2
Q

how long is the average menstrual cycle

A

23-35 days
28 most common

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3
Q

what is the ovarian cycle based of

A

hormonal changes in ovaries
follows the developemnt and release of egg

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4
Q

what is the uterine cycle based of

A

changes occuring in uterus lining
prepares for implantation of fertilised egg

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5
Q

what are the 3 main phases of the ovarian cycle

A

1) follicular phase
2) ovulation phase
3) luteal phase

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6
Q

what days of cycle is follicular phase

A

day 1-3

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7
Q

what happens in folliucular phase

A

folliculogenesis + follicide maturation

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8
Q

describe hormone levels in follicular phase

A

low oestrogen
low progesterone

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9
Q

what day of cycle is ovulation phase

A

day 14

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10
Q

what happens in ovulation phase

A

follicile releases an egg

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11
Q

describe hormone levels in ovulation phase

A

high oestrogen
this is mediated by LH surge on day 12-13 (36hr pre ovulation)

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12
Q

what day of cycle is luteal phase

A

day 15-28

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12
Q

what happens in luteal phase

A
  • follicle accumulates fatty deposits + cholesterol
  • becomes corpus luteum
  • secretes progesterone
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13
Q

describe hormone levels in luteal phase

A

high progesterone

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14
Q

what is the best marker for ovulation

A

mid luteal progesterone
this occurs at cycle length minus 7 days

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15
Q

what are the 3 stages of the uterine cycle

A

1) menses
2) proliferative
3) secretory

16
Q

what days of cycle is menses

17
Q

what happens in menses

18
Q

describe hormone levels in menses

A

low oestrogen
low progesterone

19
Q

what day of cycle is proliferative

20
Q

what happens in proliferative phase

A

uterus lining endometrium gets thick

21
Q

describe hormone levels in proliferative phase

A

high oestrogren

22
Q

what day of cycle is secretory phase

23
Q

what happens in secretory phase

A

uterine lining secrets hormones + increases mucus production

24
describe hormone levels in secretory phase
high progesterone
25
where is oestrogen produced
ovaries
26
4 functions of oestrogen
- essential for female body comp - improves bone mineral density - increases spiral arterial supply to uterus - builds up endometrium
27
where is progesterone produced
ovaries
28
3 functions of progesterone
- increases uterine mucus secretion - maintains endometrium - causes relaxation of smooth muscle
29
where is LH made
pituitary gland
30
function of LH
acts on theca cells to produce oestrogen
31
where is FSH made
pituitary gland
32
2 functions of FSH
- acts on granulosa cells to produce oestrogen - key mediator of folliculogenesis
33
when does the LH surge happen
LH surge only happens when you have isolated raised oestrogen
34
impact of COCP on HPG axis
causes negative feedback via suppresion due to raised oestrogen and progesterone
35