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B** > Haem > Flashcards

Haem Flashcards

(56 cards)

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1
Q

Schilling test

A

B12

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2
Q

Pepperport skull (lytic lesions)

A

MM, hyperparathyroidism

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3
Q

Pepperport skull (lytic lesions)

A

MM, hyperparathyroidism

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4
Q

Normocytic anaemia 6 weeks after flucloxacillin therapy

A

Autoimmune haemolytic anaemia

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5
Q

Osteopenia/lytic lesions + hypercalcaemia + rouleaux

A

Multiple myeloma

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6
Q

Target cells

A

Thalassaemia

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7
Q

Stomatocytes

A

Thalassaemia

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8
Q

Hypersegmented neutrophils

A

Megaloblastic anaemia

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9
Q

Heinz bodies and bite cells

A

G6PDH deficiency or pyruvate kinase deficiency

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10
Q

Jaundice after eating fava beans/ciprofloxacin/sulphonamide

A

G6PDH deficiency

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11
Q

Spherocytes

A

Hereditary or autoimmune haemolytic anaemia

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12
Q

Schistocytes

A

Microangiopathy (e.g. DIC) or intravascular prostheses

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13
Q

Haemolytic anaemia and aplastic anaemia after parvovirus infection

A

Sickle cell anaemia

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14
Q

Acanthocytes

A

Severe liver disease (hyperlipidaemia)

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15
Q

Cold-reacting antibodies (4)

A 
HIV
Mycoplasma
EBV
Lymphoma
13
Reticulocytes

Haemolysis

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16
Q

Anaemia and peripheral neuropathy

A

B12 deficiency

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17
Q

Young boy with swollen knee

A

Haemophilia

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18
Q

Tissue death and bleeding in a septic patient

A

DIC

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19
Q

Jaundice and kidney failure after diarrhoea in child

A

HUS

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20
Q

FTL3 mutation

A

AML

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21
Q

Marrow >20% blasts

A

AML, ALL

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22
Q

TEL-AML1 mutation

A

ALL

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23
Q

Philadelphia chromosome/BCR-ABl/9 to 22

24
Q

Reed-Sternberg cells

Study These Flashcards
A

Hodgkin lymphoma

25
Facial lymphoma caused by EBV
Burkitt's lymphoma
26
Starry sky appearance
Burkitt's lymphoma
27
Mesenteric lymphadenopathy
Non-Hodgkin lymphoma
28
CD 19, 20, 21, 23, 32, 25, 40
B cell neoplasm
29
5q mutation
Myelodysplasia
30
5q mutation
Myelodysplaia
31
Replacement of stem cells with fat in bone marrow
Aplastic anaemia
32
JAK2 mutation
Myeloproliferative disorder (PV, ET, PMF)
33
JAK2 mutation
Myeloproflierative disorder (PV, ET, PMF)
34
Pruritus, red skin and headache
PRV
35
Pruritis, red skin and headache
PRV
36
Treat with Glivec (imatinib)
CML
37
Lupus anticoagulant, anticardiolipin, anti-B2-glycoprotein-I, anti-ApOH
Antiphospholipid syndrome
38
Lupus anticoagulant, anti-cariolipin, anti-B2-glycoprotein-I, anti-ApOH
Antiphospholipid sydrome
39
Pancytopenia, thrombosis, haemolytic anaemia and positive Ham test What's the treatment?
Paroxysmal nocturnal haematuria Eculizumab
40
Hair-on-end skull, frontal and parietal bossing
Beta thalassaemia
41
Most common complication in multiple myeloma
Fractures
42
Iron-related complications of myelodysplastic diseases
Iron overload and refractory anaemia
43
Thrombosis 4 days after heparin
Heparin-induced thrombocytopenia
44
Afro-Caribbean
Sickle cell
45
Abdo pain + headaches after a respiratory infection
Sickle cell crisis
46
DRUG SE: folate deficiency (6)
``` Sulfasalazine Trimethoprim Anticonvulsants Methotrexate Metformin OCP 45 Burr cells ``` Uraemia
47
Howell-Jolly bodies
Hyposplenism
48
Lymphoplasmacytoid cells
Waldenstrom's macroglobulinemia
49
Osmotic fragility test
Hereditary spherocytosis
50
Cancer associated with pernicious anaemia
Gastric
51
Renal failure + light chains
Multiple myeloma
52
RA + splenomegaly + pancytopenia
Felty's syndrome
53
Hepatosplenomegaly + pigmentation + anaemia + pathological fractures
Gaucher's syndrome
54
Non-existent coagulation factor
VI
55
Monoclonal spikes
Multiple myeloma, MGUS
56
Bence-Jones proteins
Multiple myeloma

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