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Haem EMQ notes Flashcards

(56 cards)

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1
Q

Hypochromic, microcytic

A

Fe def

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2
Q

Macrocytic, hypersegmented neutrophils, malabsorption

A

Megaloblastic anaemia, B12 def

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3
Q

Pancytopenia, Infx, bruising, fatigue

A

Aplastic anaemia

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4
Q

RA/TB, microcytic, hypochromic, rouleaux

A

Anaemia of chronic disease

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5
Q

Mediterranean, microcytic, normal iron studies

A

Beta-thalassaemia

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6
Q

Direct antiglobulin test +ve

A

Autoimmune haemolytic anaemia

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7
Q

Heinz bodies, fava beans, bite cells

A

G6PD def

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8
Q

Jaundice, schistocytes

A

Microangiopathc haemolytic anaemia

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9
Q

Electrophoresis diagnostic, dactylitis, gutl-val6

A

Sickle cell anaemia

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10
Q

Rhesus -ve mother, severly jaundice baby

A

Haemolytic disease of the newborn

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11
Q

Post-splenectomy, inclusions w/in erythrocytes

A

Howell-Jolly bodies

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12
Q

Tear drop cells, dry-tap

A

Myelofibrosis

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13
Q

Cabot rings

A

Megaloblastic anaemia

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14
Q

FVIII def

A

Haemophillia A

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15
Q

FIX def

A

Haemophilia B

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16
Q

MAHA, Renal failure, Cranial, High temp + low plts

A

TTP

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17
Q

Sepsis/malignancy/trauma, reduced plt count, anaemia

A

DIC

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18
Q

High/normal APTT, low FVIII, low ristocetein

A

vWD

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19
Q

Thrombophilia where FV is unable to be degraded by protein C

A

FV Leiden

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20
Q

Anti-caridolipin Abs, lupus anticoagulant, SLE

A

Antiphospholipid syndrome

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21
Q

Corckscrew appearance on angiogram, smoking

A

Buerger’s

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22
Q

Persistence of FV+FVIII

A

Protein s def

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23
Q

Immunosupressed+bld transfusion, D, Rash

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A

Graft vs Host disease

24
Q

Hx of recurrent chest+GI infx + Bld transfusion

25
9;22 phili
CML
26
Tartrate-resistant acid phosphatase (TRAP)
Hairy cell leukaemia
27
Auer rods
AML
28
Japanese/Caribbean, Lymphocytosis, HyperCa
Adult T cell leukaemia
29
Smudge cells, lymphocytosis >4000
CLL
30
Starry sky
Burkitt's
31
B Sx's, painful lump after ETOH, Reed-Sternberg
Hodgkin's
32
11;14, BCL-2
Mantle cell lymphoma
33
Centrocytes, centroblasts, 14;18, BCL-2
Follicular lymphoma
34
Burning finger sensation, High Plts >600
Essential thrombocythaemia
35
Bence-Jones, lytic lesions
Multiple myeloma
36
Monocyte >1000, myeloblast >5% peripheral bld
Chronic myelo-monocytic leukaemia
37
Itching after hot bath, Hb >18, JAK2, V617F
Polycythaemia ruba vera
38
<6hrs of transfusion non-cardiogenic pulmonary oedema, granulocyte aggregation
Transfusion related acute lung injury
39
Immediately after transfusion, fever, pain in back/chest, hypotension, dark urin, DIC
ABO incompatibility
40
>24hrs after transfusion, already sensitized, falling Hb, fever, jaundice
Delayed haemolytic transfuison reaction
41
Osmotic fragility test
Spherocytosis
42
Coomb's test +ve
Autoimmune haemolytic anaemia
43
Schiling test
Vit B12 def/pernicious anaemia
44
Anti-malarial tablets/sulphonamides/fava beans causing haemolytic anaemia
G6PD def
45
Elliptocyte occuring in IDA, thalassaemia+pyruvate kinase def
Pencil cells
46
Central dense area w/ ring of pallor in Hepatic pathology/Hyposplenism/Hbglobinopathies
Target cells
47
Hb effect of EBV
Hyposplenism
48
Cause of aplastic crises in SCC
Parvovirus B19
49
Causes of colf agglutination AIHA
Cold LID lymphoproliferative disease e.g. CLL lymphomas Infections e.g mycoplasma, EBV Don't know/idiopathic
50
Donath-Landsteiner Abs, cold weather, haematuria, jaundice
Paroxysmal cold haematuria
51
Raised Ca, normal Alk phos, raised ESR, lytic lesions
MM
52
<20% blasts
Myelodysplastic syndromes
53
>20% blasts
Acute leukaemia
54
Polycythaemia, smoker
Combined Polycythaemia
55
Non classical Hodgkins lymhoma
Nodular lymphocytic
56
PML-RARA 15:17
Acute promyelocytic leukaemia

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