Heart 1 drugs

Question 1

Atenolol

Answer 1

beta blocker for pacemaker cardiomyocytes to reduce SNS activation and reduce heart rate for bradycardia

Question 2

Digoxin

Answer 2

stimulates the vagus nerve to increase Ach to bind to M2 receptors on pacemaker cells

inhibiting AC, inhibiting camp so funny channels close for bradycardia

Question 3

Ivabradine

Answer 3

physically blocks funny channels for reduced sodium influx in pacemaker cells

for bradycardia

Question 4

Atropine

Answer 4

non-selective antagonist of M2 receptor for funny channels so less parasympathetic activity when AV block

Question 5

Isoprenaline

Answer 5

non-selective agonist of Beta receptors increasing AC increasin cAMP increasing funny channel opening for AV block