HEMATOLOGY practice questions Flashcards by Jena Sy

After staining a blood smear, the RBCs appeared bluish when viewed under the microscope. The following are possible causes, except:

a. Stain or buffer is too basic
b. Inadequate rinsing
c. Inadequate buffering
d. Heparinized blood was used

b. Inadequate rinsing

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12 RBCs with basophilic stippling were seen on a blood smear. How do report this finding?

a. Positive
b. Rare, few, moderate, many
c. 1+, 2+, 3+, 4+
d. Average number / OIO

a. Positive

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Hypochromia grading: “Area of pallor is two-thirds of cell diameter”

a. 1+
b. 2+
c. 3+
d. 4+

b. 2+

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Which of the following is an example of myeloproliferative disorder?

a. Chronic myelogous leukemia
b. Myelofibrosis with myeloid metaplasia
c. Polycythemia vera
d. All of the above

d. All of the above
+ Essential thrombocythemia – excess platelet function

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Which of the following is the hematopoietic stem cell marker:

a. CD10
b. CD34
c. CD8
d. CD56

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Mixing studies
PT: increased
APTT: normal
Problem:

Problem: extrinsic pathway
Factor 7 deficiency

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Mixing studies
PT: increased
APTT: increased
Problem:

Fresh plasma: Corrected
Aged Serum : Corrected
Adsorbed Plasma: not corrected

Common pathway
Factor 10

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In a spun hematocrit, which blood component comes into direct contact with the sealant?

A. Plasma
B. Buffy coat
C Serum
D. Red Blood Cells

D. Red Blood Cells

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Which cytochemical stain is the most useful in differentiating between CML and a leukemoid reaction?

A. Prussian blue
B. LAP
C. Peroxidase
D. Fontana stain

B. Leukocyte alkaline phospatase

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The Nitroblue tetrazolium test is used to screen for what isease?

A. Chronic Myelogenous Leukemia

B. Chronic Lymphocytic Leukemia

C. Acute Lymphoblastic Leukemia

D. Chronic Granulomatous Disease

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QUEST UN #4

Considering the inheritance pattern, which disease does not belong?

A. Homophilia A

B. Homophilia B

C. Homophilia C

D. None of the above

C. Homophilia C

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Which of the following would most likely have a blood picture showing macrocytic anemia?

A. Anemia of Chronic Disease

B. Acute blood loss

C. Sideroblastic anemia

D. Folate deficiency

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Which blood tube additive is preferred for blood coagulation tests?

A. Sodium fluoride

B. Sodium citrate

C. Sodium heparin

D. Potassium oxalate

B. Sodium citrate

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A hemolytic anemia that shows red cells having a deficiency in both CD55 and CD59 in a flow cytogram:

A. G6PD Deficiency

C. Anemia of Chronic Disease

B. Thalassemia

D. Paroxysmal Nocturnal Hemoglobinuria

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In Bernard-Soulier Syndrome which of the following platelet functions are most likely defective?

A. Adhesion

B. Activation

C. Aggregation

D. Secretion

A. Adhesion

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Which elements are most likely present in the blood smear of a patient suffering from a G6PD-Deficiency?

A. Ovalocytes and Reiter Cells

B. Bite Cells and Heinz Bodies

C. Howell-Jolly Bodies and Target Cells

D. Howell-Jolly Bodies and Basophilic Stipplings

B. Bite Cells and Heinz Bodies

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Which process forms 2,3-Diphosphoglyceric acid?

A. Embden-Meyerhof Pathway

B. Rapaport-Leubering Shunt

C. Arachidonic Acid Pathway

D. Signal Transduction Pathway

B. Rapaport-Leubering Shunt

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In hypochromia grading which describes a grade of 4+7

A. Thin ring of hemoglobin

B. Area of pallor is two-thirds of the cell diameter

C. Area of pallor is three-quarters of the cell diameter

D. Area of pallor is half of the cell diameter

A. Thin ring of hemoglobin

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Which of the following is the most common complication of sickle cell disease in adults?

A. Acute Hemolytic Crisis

B. Acute Chest Syndrome

C. Vaso-occlusive Crisis

D. None of the above

C. Vaso-occlusive Crisis

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Which blood cells are usually seen in the lesions of patients with Mycosis Fungoides?

A. Eosinophils

B. Basophils

C. B-Lymphocytes

D. T-Lymphocytes

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In Flow cytometry what does the side-angle scatter measure?

A. Cell size

B. Cell granularity

C. Cell number

D. All of the above

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B. Cell granularity

In which condition does a patient’s blood appear mauve-lavender in color?

A. Iron deficiency anemia

B. Methemoglobinemia

C. Sulfhemoglobinemia

D. Carbon monoxide poisoning

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Sulfhemoglobinemia

SPICY MEDTECH REVWhich cell inclusion and RBC abnormality are consistent with G6PD Deficiency?

a. Howell-Jolly Bodies: Acanthocytes b. Cabot rings: Echinocytes

c. Heinz Bodies: Bite Cells

d. Pappenheimer bodies: Siderocytes

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c. Heinz Bodies: Bite Cells

SPICY MEDTECH REVIEW

What is the term for the removal of worn-out or damaged red cells from the circulatior

a. Lysing

b. Culling

c. Pitting

d. Splicing

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b. Culling

Disintegration of a cell by a rupture of it cell wall or cell membrane a. Lysing b. Culling c. Pitting d. Splicing

a. Lysing

Removal of cytoplasmic inclusions a. Lysing b. Culling c. Pitting d. Splicing

c. Pitting

SPICY MEDTECH REVIEW Fibrinogen is an important factor in hemostasis and is produced by the liver, Fibrinogen is a/an a. Enzyme b. Lipid c. Hormone d. Glycoprotein

d. Glycoprotein

Which of the following is considered the best site for bone marrow aspiration? a. Posterior Iliac Crest b. Anterior Iliac Crest c. Femur d. Radial bones

a. Posterior Iliac Crest

Direct Intravascular Coagulation is commonly associated with which AML according to the FAB System? a. M5 b. M4 c. M3 d. M7

c. M3

Which of the following is not measured by the Cyanmethemoglobin method? a. Oxyhemoglobin b. Carboxyhemoglobin c. Sulfhemoglobin d. All of the above

c. Sulfhemoglobin

Which of the following best describes the Apt test? a. Differentiate fetal and maternal blood b. Measures capillary fragility c. Measures hemostatic ability d. All of the above

a. Differentiate fetal and maternal blood

Screening test for theombocytopenia a. Differentiate fetal and maternal blood b. Measures capillary fragility c. Measures hemostatic ability d. All of the above

b. Measures capillary fragility

Which of the following is a rare autosomal recessive bleeding disorder characterized by a deficiency in the glycoprotein Gp1b? a. Gray Platelet Syndrome b. May-Hegglin Anomaly c. Wiskott-Aldrich Syndrome d. Bernard-Soulier Syndrome

d. Bernard-Soulier Syndrome

Rare x link bleeding disorder characterized by immunodeficiency, eczema, and thrombocytopenia a. Gray Platelet Syndrome b. May-Hegglin Anomaly c. Wiskott-Aldrich Syndrome d. Bernard-Soulier Syndrome

c. Wiskott-Aldrich Syndrome

Which of the following is a rare autosomal recessive bleeding disorder characterized by the absence or reduce number of alpha granules in plateletes a. Gray Platelet Syndrome b. May-Hegglin Anomaly c. Wiskott-Aldrich Syndrome d. Bernard-Soulier Syndrome

a. Gray Platelet Syndrome

Dominant autosomal bleeding disorder and characterized by giant platelets and granulocytes having inclusions that may look like dolhe bodies a. Gray Platelet Syndrome b. May-Hegglin Anomaly c. Wiskott-Aldrich Syndrome d. Bernard-Soulier Syndrome

b. May-Hegglin Anomaly

All of the following are Supravital dyes EXCEPT; a. Brilliant Cresyl Blue b. New Methylene Blue c. Bromocresol Green d. None of the above

d. None of the above

The correct maturation order of erythrocyte mor phologic stages is: a. Prorubricyte, rubricyte, rubriplast, metarubricyte b. Rubriblast, prorubricyte, rubricyte, metarubricyte c. Rubriblast, metarubricyte, rubricyte, prorubricyte d. Rubriblast, rubricyte, prorubricyte, metarubricyte

b. Rubriblast, prorubricyte, rubricyte, metarubricyte

What anisocytes IDA is present

MICROCYTES

What is the termed used when two distinct populations of rbcs are seen

Dimorphic population

Poikilocytosis that is usually seen in disorder of lipid metabolism and severe liver disease

Acanthocytes

Poikilocytes that Shorter spines and usually seen in anemia

Echintocytes

What poikilocytosisUsually ASEEN in hereditary ELLIPITOCYTOSIS and IDA

Elliptocytea

Poikilocytosis that is ussualy seen in burns and DIC. Thay are damaged RBCs

Schistocytes

A poikilocytosis that are ussually seen in burns and Damaged blood vessels Produced by trauma during passage to partially obstructed blood vessel

Blister cells

Helmet cell is usually seen in?

Hemolytic anemia

Bite cell is usually seen in ?

G6PD deficiency

A distorted contracted and spicylatef RBC

Spyknocytosis

It contain Hgb S and shaped as holly leaf

Sickle cell

Sickle cell is usallu seen in

Hemoglobinopathies

An rbc without a central pallor. Nearly spherical and smaller in diameter

Spherocytes

An rbc that is ussaly seen in Hereditary spherocytosis, autoimmune hemolytic anemia, and burns

Spherocytes

HEMATOLOGY practice questions Flashcards

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