Heme quick associations Flashcards
(17 cards)
Most common malignancy in children
ALL
Most common leukemia in adults
CLL
Philadelphia chromosome
CML
“smudge cells” on peripheral smear
CLL
Peripheral blasts are PAS +, TdT +
ALL
Peripheral blasts are PAS -, meyloperoxidase +, Auer rods
AML - M3
Pancytopenia in individual with trisomy 21
ALL
Associated with t(9;22)
CML, occasionally ALL
Lymphoma associated with Epstein-Barr virus (in Africa)
Burkitt’s lymphoma
- starry sky
- t(8;14)
Reed Sternberg cells, cervical lymphadenopathy, Night sweats
Hodgkins lymphoma
Bence Jones proteins, osteolytic lesions, high calcium
Multiple myeloma
t(14;18)
Follicular lymphoma
Most common lymphoma in United States
Diffuse large B cell lymphoma
t(8;14)
Burkitt’s lymphoma
Most common subtype of Hodgkin’s lymphoma
Nodular sclerosis
“starry sky pattern” due to phagocytosis of apoptotic tumor cells
Burkitt’s lymphoma
High hematocrit and hemoglobin, pruritis (especially after a hot bath or shower), Burning pain in hands or feet
Polycythemia vera