hepatology Flashcards

(33 cards)

1
Q

name some liver functions

A

Bile drainage
Blood glucose
Detoxification

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2
Q

where does bilirubin come from

A

by product of haem metabolism

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3
Q

when is ALP raised

A

biliary obstruction

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4
Q

what level does alcohol raise

A

GGT

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5
Q

synthetic liver functions

A

albumin and prothrombin time

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6
Q

G6PD deficiency

A

haemolytic anaemia

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7
Q

inheritance of G6PD deficiency

A

X linked recessive

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8
Q

G6PD deficiency precipitants

A

aspirin, antimalarial, antimicrobial, infection, illness

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9
Q

how to diagnose

A

spot test

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10
Q

if only bilirubin is down where is the problem

A

prehepatic

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11
Q

examples of prehepatic causes of low bilirubin

A

sickle cell, thalassaemia

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12
Q

gilberts inheritance

A

anutosomal dominant

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13
Q

what is antinuclear antibodies positive

A

autoimmune hepatitis

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14
Q

type one autoimmune hepatitis antibodies

A

smooth muscle antibidies

ANA

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15
Q

type two autoimmune hepatitis diagnosis

A

there are no antibodies so biopsy

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16
Q

autoimmune hepatitis treatment

A

steroids and azathioprine

17
Q

ALP is raised and gamma GT raised

A

biliary obstruction

18
Q

what to do with biliary obstruction

A

do an ultrasound to see where the blockage is

19
Q

what are anti mitochondrial antibodies positive in

A

primary biliary cholangitis

20
Q

symptoms of primary biliary cholangitis

A

pruritus and tiredness

21
Q

primary biliary cholangitis common sex

22
Q

what types of disease is primary biliary cholangitis

23
Q

primary biliary cholangitis has a long

A

latent period

24
Q

most common symptom of primary biliary cholangitis

25
why do people get bone problems in primary biliary cholangitis
prevents calcium absorption
26
Obeticholic acid treatment
Ursodeoxycholic acid and Obeticholic acid
27
byproduct of alcohol metabolism which causes liver damage
Acetaldehyde
28
NASH happens in
overweight diabetics
29
how do people ed up with liver cirrosis in NASH
fat goes to the liver and causes inflammation
30
treatment intrahepatic cholestasis in pregnancy
delivery
31
sudden high ALT
paracetamol overdose | acute hepatitis
32
causes of acute liver failure
wilsons, shock, poisoning, paracetamol, viral hepatitis
33
paracetamol overdose treatment
N acetylcysteine