herpes simplex vs. aphthous ulcers Flashcards

1
Q

what is seen mainly in children and is caused by HSV1 in most cases

A

primary herpes gingivostomatitis

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2
Q

herpes simplex.
sever primary infections have oral lesions accompanied by:

A

high fever
malaise
cervical lymphadenopathy
dehydration

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3
Q

herpes simplex.
less commonly, primary infection occurs in the young adult; in such cases infections may be from either:

A

HSV1 or HSV2

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4
Q

where do herpes gingivostomatitis/herpes simplex vesicles develop in oral cavity?

A

pharynx
palate
buccal mucosa
lips
tongue

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5
Q

herpes gingivostomatitis/herpes simplex vesicles rapidly break down into:

A

smaller ulcers and covered with exudate

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6
Q

how long do herpes gingivostomatitis/herpes simplex lesions generally resolve

A

without therapy, 2 weeks

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7
Q

HSV (does/doesnt) survive long in external environment

A

doesn’t

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8
Q

how does almost all primary HSV infections occur

A

from contact with infected person who is releasing the virus

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9
Q

HSV fever affects what % of population

A

50% (~80%)h

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10
Q

hsv fever starts what age

A

<10 from adults

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11
Q

is hsv contagious? caused by?

A

yes contagious and caused by adults

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12
Q

hsv
type 1=
type 2=

A

1=mouth lips face
2= genital outer lips and attached gingiva

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13
Q

what stage is contageous for hsv

A

vesicle stage

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14
Q

what signs of hsv arise 6-24 hours before lesions develop?
how long does it take to heal?

A

prodromal signs=tingling, itching, pain, burning

2 week

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15
Q

what does hsv look like

A

multiple fluid filled blisters
merge and collapse
yellowish crust

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16
Q

virus that is dormant in nerve cell and reoccurs with immune weakness

A

herpes simplex

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17
Q

what is considered immune weakness with herpes simplex

A

stress
fever
illness
injury
sunburn

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18
Q

infections of the thumbs or fingers
-grouped fluid filled or pus filled
usually itchy and painful

A

herpetic whitlow

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19
Q

in the past, how was primary herpetic gingivostomatitis treated?

what if diagnosed early?

A

treated symptomatically
but if diagnosed early, antiviral medications can have big influence

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20
Q

this medication is initiated during first 3 symptomatic days in a rinse-and-swallow tecnique 5x/day for 5 days.
-for primary herpetic gingivostomatitis

significant acceleration in clinical resolution is seen

A

acyclovir suspension

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21
Q

recurrent herpes labial is best treated in the

A

prodrome phase

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22
Q

what decrease the number of vesicles in herpes labialis?
clinically minimal reduction in healing time and pain

A

acyclovir ointment cream
systemic acyclovir
valacyclovir
famiciclovir

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23
Q

for patients with herpes labialis whose recurrences appear to be associataed with dental produces, a remigen of:

A

2 g of valacyclovir taken 2x on day of producer and 1 g taken 2x day following

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24
Q

what is 60% of the US population and starts around 1-20 years old?
frequency varies.

A

apthous ulcers
(canker sores)
lesions

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25
Q

prodromal tingling or burning sensation- usually 1-2 days before ulcers appears

A

apthous ulcers (canker sores)

26
Q

____ days before apthous ulcers appear, ____ days pain, ____ days healed

A

1-2 days before
3 days pain
7 days healed

27
Q

if mild disease, treatment for canker sores aka apthous ulcers is

A

topical corticosteroids

28
Q

no single triggering agent is responsible, the mucosal destruction appears to represent T-cell mediated immunologic reaction for

A

aphthous lesions

29
Q

what tends to occur along family lines?
when both parents have history, 90% children will develop

A

aphthous lesions

30
Q

3 clinical varations of aphthous lesions

A

minor
major
herpetiform

31
Q

minor major or herpetiform aphthous ulcerations.

pts. experience fewest recurences and shortest duration

A

minor

32
Q

minor major or herpetiform aphthous ulcerations.

ulcers exclusively on nonkeratinized mucosa, preceded by erythematous macule
(associated with prodromal symptoms of burning itching or stinging)

A

minor

33
Q

wont scare

A

minor

34
Q

minor major or herpetiform aphthous ulcerations.

ulcer measures 3-10mm
oval
heal withing scatting 7-14 days

A

minor

35
Q

minor major or herpetiform aphthous ulcerations.

1-5 lesions
pain often out of proportion for size

A

minor

36
Q

what oral areas affected most by minor aphthous ulcers

A

buccal and labial mucosa followed by ventral surface of tongue

37
Q

minor aphthous recurrence rate:

A

high variable, ranging from 1 ulcer every few years to 2 episodes a month

38
Q

minor major or herpetiform aphthous ulcerations.

larger than minor 1-3 cm

A

major

39
Q

minor major or herpetiform aphthous ulcerations.

have longest duration per episode

A

major

40
Q

ulcers deep and can take 2-6 weeks toheal

A

major

41
Q

lesions very from 1-10

A

major

42
Q

onset is after puberty

A

major

43
Q

minor major or herpetiform aphthous ulcerations.

greatest number of lesions and most frequent recurrence

A

herpetiform

44
Q

lesions small 1-3 mm

A

herpetiform

45
Q

many as 100 ulcers present in single occurrence

A

herpetiform

46
Q

lesions bear superifical resemblance to primary HSV due to

A

herpetiform
due to small size and how many

47
Q

common for individual lesions to coalesce into larger irregular ulcerations

A

herpetiform

48
Q

heals within 7-10 days

A

herpetiform

49
Q

many patients affect almost constantly for periods as long as 3 years

A

herpetiform

50
Q

any oral mucosal involved

A

herpetiform

51
Q

minor major or herpetiform aphthous ulcerations.

female predominance

A

herpetiform

52
Q

onset is adulthood

A

herpetiform

53
Q

minor major or herpetiform aphthous ulcerations.

<1cm and shallow

A

minor

54
Q

minor major or herpetiform aphthous ulcerations.

> 1 cm and many scar when heal

A

major

55
Q

minor major or herpetiform aphthous ulcerations.

more numerous and vesicular

A

herpetiform

56
Q

aphthous ulcers treatment.
symptomatic:

A
  1. viscous benzocaine
  2. orajel, anbesol
57
Q

aphthous ulcers treatment.
local anti-inflammatory:

A

kenalog in orabase paste 2-4x day

58
Q

aphthous ulcers treatment for sealing agent

A

ameseal

59
Q

canker sores (aphthous ulcers)
only fda approved tx
paste=barrier
apply 2-4x day
must start early in prodromal stage!!!

A

aphthasol

60
Q
A