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Farma > Hipoglucemiantes orales > Flashcards

Hipoglucemiantes orales Flashcards

1
Q

secretagogos bloqueo de canales de K ATP

A

sulfonilureas

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2
Q

EA de sulfonilureas

A

aumento de peso . hiperinsulemias nausea cefalea ictericia agranulocitosis

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3
Q

CI de sulfonilureas

A

DM1 embarazo lactancia insuficiencias pierden efecto

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4
Q

menciona las sulfonilureas de primera generacion

A

clorpropamida talozalamida tolbutamida

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5
Q

EA sulfa disminuye el Na al potenciar ADH mayor riesgo de hipoglusemia

A

Clorpropamida

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6
Q

sulfa con absorbcion mas lenta

A

Tolazamida

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7
Q

mas segura en pacientes ancianos

A

tolbutamida

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8
Q

sulfas de segunda generacion

A

Glibenclamida Glipizida Glimeprida

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9
Q

tambien segura en ancianos EA mas rieso cardiovascular

A

Glibenclamida

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10
Q

alimentos retrasan absorcion 30 min antes del desayuno

A

Glipizida

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11
Q

menciona las biguadinas

A

Metformina

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12
Q

activa AMP cinasa 1 en DM2 eficas con monoterapia y glipzida , glibenclamida piglitazona NO aumento de peso Tx ovario poliquistico EA diarrea o deficiencia B12

A

Metformina

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13
Q

tiazolindinedionas

A

Rosiglitazona Pioglitazona

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14
Q

son agonistas selectivos del receptor PPAR y regula el metabolismo de carbohidratos y lipidos

A

tiazolindinedionas

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15
Q

disminuye 1- 1.5 HbA1c en DM2 riesgo de EVC aumenta fracturas en mujeres

A

Rosiglitazona

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16
Q

aumenta riesgo de IAM y mejora perfil de lipidos

A

Pioglitazona

17
Q

menciona las Amilana

A

Pramlintida

18
Q

retrasa el vaciamiento gastrico y da saciedad Tx DM1 DM2 sin buen control de insulina EA nausea VomitoHipoglucemia y gastroparecia

A

Pramlintida

Farma (30 decks)

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