histology of the skin

Question 1

the epidermis consists of _____cells; the dermis is______

Answer 1

stratified squamous keratinized epithelium

Question 2

most common cell type of the epidermis

Answer 2

keratinocytes

Question 3

fxn of keratinocytes

Answer 3

continuous skin renewal by mitotic activity

Question 4

what are the APC of the epidermis

Answer 4

langerhans cells

Question 5

langerhans cells are found in which layer of epidermis

Answer 5

stratum spinosum

Question 6

membrane bound birbeck granules

Answer 6

langerhans cell cytoplasm

Question 7

what type of cells are tactile receptors ; what layer?

Answer 7

merkel cells; stratum basale

Question 8

melanocytes arise from what type of cells

Answer 8

neural crest

Question 9

what layer are melanocytes in?

Answer 9

stratum basale + superficial dermis

Question 10

T or F: darker skinned ppl have more melanocytes

Answer 10

FALSE, same #; they just have incr tyrosinase activity

Question 11

d/t complete loss of melanocytes from autoimmunity or self destruction of melanocytes

Answer 11

vitiligo

Question 12

whn melanocytes do not synthesize melanin d/t defect in tyrosinase

Answer 12

albinism

Question 13

which cell layer in epidermis is responsible for waterproofing

Answer 13

stratum granulosm

Question 14

most intense mitotic activity occurs at what level of epidermis

Answer 14

stratum basale

Question 15

thin skin contains which layers (3)

Answer 15

1. stratum corneum
2. stratum spinosum
3. stratum basale

Question 16

what is the CT layer of the skin?

Answer 16

dermis

Question 17

mechanoreceptors in papillary layer of dermis

Answer 17

meissner corpuscle

Question 18

what type of collagen forms langer’s lines

Answer 18

type 1 collagen in the reticular layer of the dermis

Question 19

what cells detect pressure, vibration in the reticular layer of the dermis

Answer 19

pacinian corpuscles

Question 20

what cells detect tensile forces in the reticular layer of teh dermis

Answer 20

ruffini corpuscles

Question 21

simple coiled tubular glands scattered throughout skin that squirt sweat

Answer 21

eccrine sweat glands

Question 22

eccrine sweat glands: cell type of secretory segment is _______; of duct cells is _______

Answer 22

simple cuboidal to low columnar; stratified cuboidal epithelium

Question 23

sweat glands in In axilla, areola of nipple and anal region

Answer 23

apocrine sweat glands

Question 24

eccrine and apocrine sweat glands use _____secretion; vs sebaceous glands that use _______secretion

Answer 24

merocrine; holocrine

Question 25

nail bed consists of what cell types?

Answer 25

stratum basale; stratum spinosum

Question 26

what is the eponychium?

Answer 26

cuticle