Histology/Skin Structure Flashcards

(41 cards)

1
Q

name the five layers of the epidermis

A
corneum
lucidum
granulosum
spinosum
basale
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2
Q

what are the two layers of the dermis

A

reticular and papillary

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3
Q

name the four cells in the epidermis

A

keratinocytes
melanocytes
langerhans
merkel cells

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4
Q

name the two types of connections used by keratinocytes in the basale

A

desmosome and hemidesmosome

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5
Q

what are the four layers in thin skin epidermis?

A

all except the lucidum

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6
Q

what layer of epidermis has melanocytes?

A

in the stratum basale

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7
Q

what layer of epidermis has langerhans cells?

A

in the stratum spinosum

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8
Q

how can you pick out langerhans cells on histo?

A

pale cells in the spinosum layer that have comma like processes

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9
Q

what do langerhans cells have in them?

A

birbeck granules

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10
Q

what type of cell is a langerhan cells?

A

dendritic APC cells

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11
Q

what layer are merkel cells in? what is their function?

A

basale

sensory mechanoreceptors

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12
Q

what do keratinocytes in the stratum spinosum have? what does this lead to?

A

membrane coating granules that release lipids to help skin be impermeable

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13
Q

what do keratinocytes in the granulosum have? what does it help with?

A

keratohyaline granules that help bind the keratinocytes together

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14
Q

what two locations have thick skin?p

A

palms and soles

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15
Q

what type of collagen is in the dermis?

A

mainly type 1

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16
Q

name the sweat gland types

A

sebaceous
apocrine
eccrine

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17
Q

what type of structure is a eccrine sweat gland?

A

simple coiled tubular

18
Q

name the three cells of eccrine sweat glands

A

dark
clear
myoepithelial

19
Q

what do dark cells of eccrine glands release?

A

mucinogen rich granules

20
Q

what do clear cells in eccrine sweat glands release?

A

watery electrolyte rich material

21
Q

what is function of myoepithelial cells?

A

to contract and help release of glands

22
Q

what is role of apocrine sweat gland? where are they located?

A

large specialized glands..in axilla and perianal regions

23
Q

what do sebaceous glands secrete?

A

oily secretion

24
Q

where are sebaceous glands located?

A

next to necks of hair follicles and release ther

25
what is the structure of sebaceous glands?
branched acinar glands with lobular appearance
26
name the three gland secretion mechansims
holocrine apocrine merocrine
27
what is holocrine secretion? which gland does this?
release of entire cell..done by sebaceous glands
28
what is merocrine secretion? which gland does this?
exocytosis...done by eccrine glands
29
what is apocrine secretion? which gland does this?
release part of apical cytoplasm...done by apocrine glands
30
what is the muscle that causes chill bumps?
arrector pili muscle
31
name the two corpuscles in the skin to know
meissners and pacinian
32
what is the role of the meissners corpuscle
fine touch perception
33
where is meissners corpuscle located in skin layers?
dermal papillae of thick skin, eyelids lips nipples
34
what are dermal papillae?
the tall branches that overlap with the epidermal pouches
35
what is the function of the pacinian corpuscle?
perceive pressure touch and vibrations
36
where are pacinian corpusles located in the skin layers?
dermis and hypodermis
37
what is an important protein in the granular layer of the epidermis? what is its role?
filaggrin..retains water in keratinocytes
38
name the two cells in the dermis layer
mast cells and fibroblasts
39
what cell in the dermis is in charge of immediate type hypersensitivity reactions?
mast cells
40
what cell in the epidermis is in charge of rashes from poison ivy?
langerhans or APCs
41
what makes up the subcutis layer?
FAT