Histopathology CNS Cases (Week 5--Vinters) Flashcards Preview

Block 5: Neuroscience > Histopathology CNS Cases (Week 5--Vinters) > Flashcards

Flashcards in Histopathology CNS Cases (Week 5--Vinters) Deck (5):
1

Two causes of stroke

1) Atherosclerosis --> infarcts by direct occlusion of an artery feeding specific area of the brain

2) Thromboemboli (artery-to-artery emboli) --> focal brain necrosis --> permanent focal neurological deficit

2


Examples of focal neurologic deficits


Aphasia

Hemiparesis

Hemiplegia

3


How do you detect Lewy bodies (characteristic of Parkinson's disease)


Use antibody to alpha synuclein in nerve cells

4


Two lesions that accumulate in CNS of patients with Alzheimer's


Senile "neurotic" plaques

Neurofibrillary tangles

Note: both of these contain A-beta protein

5

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