Hodgkin Lymphoma

Question 1

Classic pathologic IHC findings

Answer 1

CD15+
CD30+
PAX-5+
CD79a-
CD20-

Question 2

Hodgkin Lymphoma is associated with what infection?

Answer 2

EBV in 30-40% of cases

Question 3

What are the IHC findings in nodular lymphocyte-predominant Hodgkin lymphoma?

Answer 3

CD19+, CD20+
CD15-, CD30-

Question 4

Important prognostic factors for Hodgkin Lymphoma

Answer 4

IPS for advanced disease
Age > 45, male, Hgb < 10.5, leuk > 15k, ALC < 600, albumin < 4, stage IV disease.
IPS > 3 have inferior outcomes.