Homeostasis and Biological Rhythms Flashcards

(37 cards)

1
Q

What is homeostasis?

A

The maintenance of a stable internal environment

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2
Q

What do homeostatic mechanisms act to do?

A

Counteract the changes in the internal environment

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3
Q

At what level does homeostasis occur?

A

All levels -

  • Cellular
  • Organ/system
  • Whole body
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4
Q

What factors does homeostasis control?

A
  • Supply of nutrients
  • Supply of oxygen
  • Blood flow
  • Body temperature
  • Removal of waste
  • Control of CO2
  • pH
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5
Q

What does failure of homeostasis lead to?

A

Disease

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6
Q

What are the components of the control systems in the body?

A
  1. Communication
  2. Control centre
  3. Receptor
  4. Effector
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7
Q

What are the main communication pathways in the body?

A
  • Nervous system
  • Endocrine system
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8
Q

What does the nervous system use?

A

Hormones

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9
Q

What is paracrine control?

A

Local release (via ducts/exocrine) and action

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10
Q

What is autocrine control?

A

When agents are released by a cell which affects the releasing cell

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11
Q

What can the peripheral nervous system be divided into?

A

The afferent branch (sensory input) and the efferent branch (motor output)

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12
Q

What does the control centre do?

A
  • Establishes the reference set point
  • Analyses the afferent input
  • Dtermines the appropriate response
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13
Q

Give two important control centres in the brain

A
  • Diencephalon
  • Medulla oblongata
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14
Q

Where is the dicephalon located?

A

In the hypothalamus

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15
Q

Where is the medulla oblongata located?

A

In the brain stem

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16
Q

What is the hypothalamus involved in the regulation of?

A

The endocrine system

17
Q

What are regions of the medulla involved in the control of?

A
  • Ventilation
  • Cardiovascular system
18
Q

What are receptors required for in the bodies control systems?

A

Detect stimuli such as changes in the internal environment

19
Q

Give two examples of receptors

A
  • Chemoreceptors
  • Thermoreceptors
20
Q

What are receptors usually made of?

A

Specialised nerve endings

21
Q

How do sensors communicate input to the control centre?

A

Via the afferent nerves

22
Q

What do effectors do?

23
Q

What happens to the output produced by the control centre?

A

It is communicated via efferent pathways to the effectors

24
Q

Give an example of an effector?

A

Sweat glands, which can be activated to produce more sweat, causing heat loss

25
Give an example of a control system in the body
The hypothalamic-pituitary-adrenal axis
26
What is it called when the set point for homeostasis varies over time?
Biological rhythm
27
Give an example of a level varies during the day
Level of the hormone cortisol
28
When does cortisol levels reach their peak?
Around 7am
29
When are cortisol levels at their lowest?
About 7pm
30
What is it known as when levels vary over roughly a 24 hour cycle?
Circadian rhythm
31
What is the clinical relevance of the circadian rhythm of cortisol?
The time should always be noted when taking a sample of blood for cortisol measurement, and when repeating a measurement it should be taken at the same time of day. Alternatively, the 24 hour urinary excretion of cortisol can be measured
32
Draw a diagram illustrating the HPA axis
33
What is the clinical condition of hypoactivity of the adrenal cortex called?
Addisons disease
34
What effect does Addisons disease have on blood cortisol levels?
Low blood cortisol
35
What is the clinical condition of hyperactivity of the adrenal cortex called?
Cushing's syndrome
36
What effect does Cushings syndrome have on blood cortisol?
High blood cortisol
37
How can temperature be used as a marker of ovulation?
Women's core body temperature varies during the menstural cycle, and a sudden increase in core body temperature can be used as a marker of ovulation