How Synapse Works Flashcards

(37 cards)

0
Q

Most important ions if nervous system

A

Sodium na+
Potassium k+
Chloride cl-

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1
Q

What are ions

A

Atoms or groups of atoms which have gained or lost and electron and are this either positively or negatively charged

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2
Q

What do membranes have that let some things in but mostly they work to keep some things out

A

Ion channels that are topically closed

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3
Q

Resting. Potential

A

If the cell isn’t doing anything and it’s channels are closed

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4
Q

Resting potential is always in a state of

A

Imbalance- polarized

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5
Q

Resting Potential of the cell membrane is

A

Negatively charged

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6
Q

Imbalance of membrane

A

Polarization

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7
Q

Inside of cell is always

A

Negative

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8
Q

Outside of cell is always

A

Positive relative to the inside of the cell

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9
Q

The only way to send an impulse from that cell is to disrupt the

A

Polarized status

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10
Q

How to change the polarized state of cell membrane at rest

A

We need a spike in electrics voltage to disrupt things
The electric me voltage will be coming in from an axon to a dendrite
When that happens, the electricke signal MIGHT be string enough to disrupt resting potential

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11
Q

How disrupt RP

A

If the signal is sufficient to reach/breach the threshold

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12
Q

What does reach threshold mean

A

The degree of electricke charge must be string enough to change the permeability of the cell membrane

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13
Q

Why need to change permeability

A

Because the cell membrane is generally closed/at rest/ polarized

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14
Q

Once signal reach/beach threshold

A

Sodium/potassium pump go to work to disrupt the polarization

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15
Q

Disrupt polarization

A

Sodium rushes in

It wants a more negative environment inside

16
Q

Disrupt polarization

A

Potassium rushes out

It Wants a more positive environment outside

17
Q

Na in and k out will change…

A

The polarization (resting state of imbalance) between the inside and outside of cell

18
Q

What does it’s all or nothing mean

A

The cell either fires or is doesn’t based on whether or not its threshold has been reached and breached
Most thresholds for firing requires a 5-10 mV change in polarity

19
Q

Changing the polarization of a cell has two outcomes

A

Depolarization
Hyperpolarization
Which ever happens the process is quick, fluid, explosive
All gates open and close or … Not

20
Q

Depolarization

A

Fire the impulse

Membrane is balanced

21
Q

Hyper polarization

A

Do NOT fire the impulse

Keep imbalanced and closed

22
Q

If depolarization occurs and sodium rushes in, disrupting. The rating potential/depolarizer state if the cell then…

A

The impulse will transmit down the axon of that cell body

Called action potential

23
Q

Action potential occurs

A

At the moment a neuron send an impulse down its axon. It is also called a spike or impulse

24
The cell returns to its resting potential, due to the work of
Potassium channels
25
Is like the bouncer
Na/k pump to get na out and k back in--> refractory period
26
During polarization the rest if state if the cell membrane is
Negative
27
Polarization | Surge in voltage from an incoming impulse cause
Change in this resting potential (either more positive, or more negative. Than it's resting negativity From here two options
28
Depolarization steps
Some Neurotransmitters cause less negativity inside the cell this exciting the cell to fire a response Initiates the action potential Fire! Aka excitatory post synaptic potential
29
Hyper polarization steps
Some Neurotransmitters cause less negativity inside the cell thus inhibiting any potential firing of a response Inhibits the action potential Do not fire Aka inhibitory post synaptic potential
30
Purpose of inhibit
Basal ganglia either excite neurons to fire to create more necessary movements Or inhibit because too much movement
31
T/f only shave one action potential occurring at a time
T
32
During that time the voltage gated ion channels are opening to allow na to rush in
And the they become inactive
33
Inactive is also known as
Absolute refractory period | Nothing else can happen then. No other action potential can take place
34
When k starts to rush out (no more na going in, it's done) when k starts to rush out...
The ion channels start to depolarize back to being closed
35
During this k rush and efforts to depolarize membrane (go back to closed/resting potential)
You could stimulate another action potential
36
Only do this if the stimulus is white strong because you have not yet closed all of the ion channels. Called
Relative refractory period