Human Cells Unit 1 KA 1 Flashcards

Division and Differentiation

1
Q

What are Somatic cells?

A

Somatic cells are body cells that are not involved in reproduction

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2
Q

How do Somatic cells divide?

A

Somatic cells divide by Mitosis to form more somatic cells

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3
Q

How many chromosomes are in a Somatic cell?

A

There are 46 chromosomes in a Somatic cell, they are diploid

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4
Q

Somatic cells differentiate to form different body tissue type - (4)

A

1) Epithelial
2) Connective tissue
3) Muscle tissue
4) Nervous tissue

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5
Q

What does a Germaline cell do?

A

A Germaline cell produces Gametes

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6
Q

Where are Germaline cells found?

A

Germaline cells are found in the ovaries (f) and testes (m)

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7
Q

How do Germaline cells divide?
What do they form? (2)

A

1) Mitosis - more diploid germaline cells
2) Meiosis - haploid gametes

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8
Q

What does division by Meiosis produce?

A

Division by Meiosis produces haploid gametes, reducing the number of chromosomes from 46 -> 23

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9
Q

How many divisions are there in Meiosis?
How many haploid gametes does this produce?

A

There are two divisions in Meiosis, four haploid gametes are produced

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10
Q

What is Cell Differentiation?

A

Cell differentiation is when an unspecialised cell becomes specialised to carry out a specific function

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11
Q

How does a cell become Specialised?

A

A cell becomes specialised by expressing certain genes to produce proteins characteristic for that type of cell

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12
Q

What are some examples of differentiated cells? (4)

A

1) Sperm cells
2) Goblet cells
3) Nerve cells
4) Red blood cells

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13
Q

What are Stem cells?

A

Stem cells are cells that are unspecialised and have the ability to differentiate into specialised cells

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14
Q

What are the two roles of Stem cells?

A

1) Self-renew (make copies of themselves)
2) Differentiate (make other types of cells)

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15
Q

What are the two different types of Stem cells?

A

1) Tissue stem cells
2) Embryonic stem cells

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16
Q

Which type of Stem cell is Multipotent?

A

Tissue stem cells are Multipotent - they can differentiate to produce a limited range of cell types

17
Q

Which type of Stem cell is Pluripotent?

A

Embryonic stem cells are Pluripotent - they can differentitate to make ALL cell types

18
Q

Where are Tissue stem cells found? (8)

A

1) Brain
2) Cornea
3) Testicles
4) Breast
5) Bone marrow
6) Intestines
7) Muscles
8) Skin

19
Q

Where are Embryonic stem cells found?

A

Embryonic stem cells are found in a human blastocyst

20
Q

Why do Tissue stem cells only differentiate to produce a limited range of cell types?

A

Tissue stem cells can only differentiate to produce a limited range of cell types because some of the genes in them have already been switched off

21
Q

Why can Embryonic stem cells differentiate to produce ALL cell types?

A

Embryonic stem cells can differentiate to produce ALL cell types because all the genes in them are still switched on

22
Q

What are Therapeutic uses of Stem cells? (2)

A

1) Corneal Repair
2) Regeneration of damaged skin

23
Q

What are the Research uses of Stem cells? (4)

A

Provides information on -
1) Cell growth
2) Differentiation
3) Gene regulation

Can be used as model cells to study how diseases develop and for drug testing

24
Q

What are Cancer cells?

A

Cancer cells are cells which divide excessively to produce a mass of abnormal cells called a tumour

25
Q

Why do Cancer cells divide excessively?

A

Cancer cells divide excessively because they do not respond to regulatory signals

26
Q

What happens if the cells within the tumour fails to attach?

A

If cells within the tumour fail to attack, they can spread through the body forming secondary tumours