Hypersensitivity - allergy Flashcards
1
Q
What is an allergy
A
Immunologically based sensitivity
- specific immune response to allergen
- Not dose dependent
- reaction will change on subsequent exposure
2
Q
What is Toxicity
A
A non-immunologically based reaction
- Non-specific
- Dose dependent
- Reaction will be similar on exposure
3
Q
4 routes of entry to allergies
A
- skin & mucosa
- injection
- inhalation
- ingestion
4
Q
How many types of hypersensitivity is there
A
4 types
- immediate IgE mediated - anaphylaxis
- Auto antibody mediated
- Immune complexes
- T cell mediated -delayed hypersensitivity
5
Q
What type of hypersensitivity is anaphylaxis
A
Type 1 - immediate IgE mediated
In people with allergies IgE (immunoglobulin the antibody) in response to food/substance/medication
6
Q
What type of hypersensitivity is T cell mediated - delayed hypersensitivity
A
Type 4
