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endocrine > hypothyroisism > Flashcards

hypothyroisism Flashcards

1
Q

autoimmune condition usually seen in women over 60?

A

hashimotos

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2
Q

hashimotos associated with high titres of auto antibodies. which auto antibodies ?

A

TRAB blocking
anti thyroid peroxidase
anti thyroglobulin

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3
Q

other causes of hypothyroidism?

A

atrophic thyroiditis
iodine deficiency
iatrogenic

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4
Q

two goitrous causes of hypothyroidism?

A

hashimotos, iodine deficiency

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5
Q

non goitrous causes ?

A

ablation, atrophic thyroidits, congenital

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6
Q

iatrogenic causes of hypothyroidism?

A

post thyroidectomy, post radiotherapy to thyroid,

drugs - Lithium, Amiodarone

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7
Q

SYMPTOMS - GI

A

contipation

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8
Q

GU?

A

menorrhagia, infertility

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9
Q

MSK

A

weakness, cramps, myalgia

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10
Q

psychiatric ?

A

depression, reduced memory, dementia

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11
Q

general?

A

weight gain, tiredness, fatigue, peri orbital swelling

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12
Q

derm

A

dry skin, course hair, hair loss, so of outer third of eyebrow

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13
Q

neurology?

A

ataxia - slow, relxing reflexes

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14
Q

general?

A

cold peripheries, facial puffiness, non pitting oedema on hands and feet

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15
Q

low T3?T4, high TSH?

A

primary

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16
Q

low TSH, low T3/T4?

A

secondary

17
Q

subclinical hypo?

A

high TSH, normal T3/T4

18
Q

management of hypo?

A

levothyroxine

19
Q

what is levothyroxine?

A

T4

20
Q

difference in doses between younger and older patients?

A

elderly get half the dose

21
Q

what do you need to monitor when on levothyroxine?

A

TSH

22
Q

what is myxoedema coma

A

ultimate state of hypothyroidism before death

23
Q

management of myxoedema coma?

A 
TFT/baseline bloods
correct hypoglycaemia 
actively warm patient 
give T3 infusion 
give hydrocortisone
24
Q

when would you get myxoedema coma and how would you treat it?

A

MI
infection
untreated hypothyroid
post pituitary surger

endocrine (27 decks)

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