passmed Flashcards

1
Q

what is cimetidine?

A

H2 receptor antagonist (inhibits stomach acid production)

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2
Q

the p’s pf raised prolactin?

A
pregnancy 
prolactinoma 
physiological 
PCOS 
primary hypothyroidism
phenothiazines (metaclPramide, domPeridone)
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3
Q

HbA1c - does it have a place in diagnosis of type 1 diabetes?

A

no

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4
Q

what diabetic medication must be avoided in patient with history of heart failure?

A

pioglitazone

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5
Q

what do DDP4 inhibitors do to weight?

A

weight neutral

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6
Q

give an example of a DPP4 inhibitor?

A

sitagliptin (griffin) (saxophone)

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7
Q

pioglitazone side effects?

A

weight gain
liver impairment
increased fracture risk
causes fluid retention (can’t use in heart failure)

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8
Q

when is piogitazone contraindicated?

A

in heart failure - causes fluid retention

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9
Q

most common side effect in sufonylureas?

A

weight gain (fat bride)

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10
Q

other side effects of sufonylureas?

A

SIADH
bone marrow suppression
liver damage
peripheral neuropathy

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11
Q

what is a known complication of carbimazole

A

agranulocytosis

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12
Q

what would a patient develop with ahranulocytosis?

A

sore throat or fever

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13
Q

which drugs may reduce hyperglycaemic awareness?

A

beta blockers

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