I: Male Pathology

Question 1

______ prostate zone: inverted cone with base at the base of the prostate and apex at the verumonatorum

Answer 1

Central

Question 2

______ prostate zone: Surrounding zone posteriorly, laterally, and apically

Answer 2

Peripheral

Question 3

______ prostate zone: two lobes surrounding prostatic urethra laterally and anteriorly

Answer 3

Transition

Question 4

_______: squamous cell CIS involving genital skin

Answer 4

Bowen’s Disease

Question 5

_______: squamous cell CIS involving mucosal surface of uncircumcized glans penis

Answer 5

Erythroplasia of Queyrat

Question 6

______: site of prostatic urethra merging with ejaculatory ducts, at which the urethra makes a 35-degree bend

Answer 6

Verumonatorum

Question 7

Best marker for detection, staging, and monitoring of patients with prostate cancer

Answer 7

PSA

Question 8

BPH most commonly occurs in the _____ zone.

Answer 8

Transition

Question 9

Most common cause of infectious epididymitis/orchitis in children

Answer 9

Gram negative rods

Question 10

Most common cause of infectious epididymitis/orchitis in sexually active adults

Answer 10

Neisseria, Chlamydia

Question 11

Most common cause of infectious epididymitis/orchitis in the elderly

Answer 11

Enterobacteria

Question 12

Prostate cancer is assigned a _____ grade based on similarity of glandular architecture to normal

Answer 12

Gleason

Question 13

Prostatic adenocarcinoma most commonly occurs in the ____ zone.

Answer 13

Peripheral

Question 14

Varicocele more oftenly affects the ___ testis.

Answer 14

left

Question 15

Which pathology? Aberrant phagocytic process with bacterial fragments calcifying within phagocytes

Answer 15

Malakoplakia

Question 16

Which pathology? Arrest in germ cell development, thickening of basement membrane, Leydig cell hyperplasia, hyaline replacement

Answer 16

Cryptorchidism

Question 17

Which pathology? Caseating granulomas part of systemic disease

Answer 17

Tuberculous Orchitis

Question 18

Which pathology? Difficulty starting/stopping urination, increased urinary frequency, nocturia

Answer 18

BPH/adenocarcinoma

Question 19

Which pathology? Diffuse mononuclear interstitial infiltrate rich in plasma cells, obliterative endarteritis, +/- gummas

Answer 19

Syphilis

Question 20

Which pathology? Dilation and tortuosity of veins in pampiniform plexus

Answer 20

Varicocele

Question 21

Which pathology? GCT in older men, cells resemble primary and secondary spermatocytes

Answer 21

Spermatocytic seminoma

Question 22

Which pathology? GCT that may cause gynecomastia and precocious puberty, granular eosinophilic cytoplasm with intracytoplasmic crystals

Answer 22

Leydig Cell Tumor

Question 23

Which pathology? GCT that secretes alpha-fetoprotein

Answer 23

Yolk Sac Tumor

Question 24

Which pathology? GCT with fish-flesh appearance

Answer 24

Seminoma

Question 25

Which pathology? GCT with frequent metastases, secretes beta-hCG

Answer 25

Choriocarcinoma

Question 26

Which pathology? GCT with heterogenous elements; good prognosis in children/variable in adults

Answer 26

Teratoma

Question 27

Which pathology? Inspissation of secretions to form sand-like substance in prostate

Answer 27

corpora amylacea

Question 28

Which pathology? Lymphocytic and plasma cell infiltration of prostate parenchyma

Answer 28

Chronic prostatitis

Question 29

Which pathology? Mononuclear inflammatory infiltrate with interstitial edema, infertility uncommon, usually subsequent to parotid involvement

Answer 29

Mumps orchitis

Question 30

Which pathology? More aggressive than seminomas, small tumors; large hyperchromatic pleomorphic nuclei and indistinct cytoplasm with frequent mitoses

Answer 30

Embryonal carcinoma

Question 31

Which pathology? Most common cancer in males

Answer 31

Prostatic Adenocarcinoma

Question 32

Which pathology? Most common penile cancer

Answer 32

Squamous Cell Carcinoma

Question 33

Which pathology? Most common testicular tumor in infants/children, loose/maze-like network of cells

Answer 33

Yolk Sac Tumor

Question 34

Which pathology? Most common testicular tumor in men over age 60

Answer 34

Lymphoma

Question 35

Which pathology? Most common type of germ cell tumor

Answer 35

Seminoma

Question 36

Which pathology? Neoplastic condition arising from condylomatous lesion with local invasion

Answer 36

Verrucous carcinoma

Question 37

Which pathology? Neutrophilic inflammation of prostate due to S. aureus, E. coli, or enterobacteria most commonly

Answer 37

Acute prostatitis

Question 38

Which pathology? Nodular aggregation of histiocytes containing calcified intracytoplasmic inclusions (_____ bodies)

Answer 38

Malakoplakia; Michaelis-Gutmann

Question 39

Which pathology? Occur in young men (15-35) with painless testicular enlargement

Answer 39

Germ Cell Tumor

Question 40

Which pathology? Placental differentiation with cytotrophoblasts and syncytiotrophoblasts

Answer 40

Choriocarcinoma

Question 41

Which pathology? Tubular sclerosis, Leydig cell hyperplasia, infertility

Answer 41

Klinefelter Syndrome

Question 42

Which pathology? Tuffed, papillary, or cribriform proliferation of atypical cells surrounded by basal cell layer (Prostate)

Answer 42

Prostatic Intraepithelial Neoplasia

Question 43

Which pathology? Undescended testes located anywhere along the path of descent

Answer 43

Cryptorchidism

Question 44

Which pathology? Uniform population of large polygonal cells with distinct cell membrane, clear cytoplasm, central nucleus; may have hCG-producing giant cells

Answer 44

Seminoma

Question 45

Which pathology? Variable glandular and stromal hyperplasia with dilatation of glands and papillary infoldings (Prostate)

Answer 45

BPH

Question 46

Which pathology? Yellowish or inapparent nodule, proliferation of cuboidal or columnar cells in a single-layered epithelium (prostate)

Answer 46

Adenocarcinoma

Question 47

Which typically occurs first: epididymitis or orchitis?

Answer 47

Epididymitis