Ibuprofen Flashcards
1
Q
Drug class
A
Non-steroidal anti-inflammatory drug (NSAID)
2
Q
Pharmacology
A
Is a non-selective NSAID that inhibits the synthesis of prostaglandins resulting in analgesic, antipyretic & anti-inflammatory actions
3
Q
Metabolism
A
Metabolised by the liver & excreted mainly by the kidneys
4
Q
Indications
A
Moderate pain due to acute inflammation & tissue injury
5
Q
Contraindications
A
- Allergy and/or adverse drug reaction to any NSAID
- Current GI bleeding OR peptic ulcers
- Dehydration AND/OR hypovolaemia
- Renal impairment
- NSAID induced asthma
- Heart failure
- Pregnancy
- Angiotension converting enzyme (ACE) inhibitor OR Angiotension II receptor blocker (ARBs)
- Pts <13 OR ≥ 65yrs
- Pts taking anticoagulants
- Diuretic Rx
6
Q
Precautions
A
- Asthma
- Hepatic dysfunction
- Hx GI bleeding or peptic ulcers
7
Q
Side effects
A
- Nausea
- Dyspepsia
- GI bleeding
- Dizziness
8
Q
Presentation
A
200mg tablet
9
Q
Onset
Duration
A
O: ~15mins
D: 4-6hrs
10
Q
Routes of administration
A
Per oral (PO)
*shortly following food/milk
11
Q
Adult dosages
A
PO 200-400MG
*not within 6hrs of previous dose
