ID Review Session Flashcards

1
Q

What are the 5 lactose-fermenting, Gram-negative rods?

A

E coli
Klebsiella
Enterobacter

Citrobacter
Arizona (Salm.)

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2
Q

Mucoid vs non-muoid lactose-fermenters?

A

E coli is flat

Klebsiella and Enterobacter are mucoid

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3
Q

What color are alpha-hemolytic strep colonies on blood-agar plates?

A

Green

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4
Q

What color are beta-hemolytic strep colonies on blood-agar plates?

A

Clear the bood

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5
Q

What color are gamma-hemolytic strep colonies on blood-agar plates?

A

no clearing

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6
Q

What are the two most important species of Gram-positive rods we need to know about?

A

Clostridium- large; spores;

Listeria- small; meningitis, spontaneous abortions, diarrhea; often pregnant or immunocompromised

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7
Q

What bacteria should pneumonia make you think of?

A
Strep pneumo
H. influenzae
Moraxella
Mycobacterium tuberculosis
Legionella pneumophila
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8
Q

What bacteria should skin/soft tissues make you think of?

A

Staph aureus
Group A Strep
Group B Strep
Clostridium perfringens

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9
Q

What bacteria should enteritis make you think of?

A

Vibrio cholerae

Enterotoxigenic E coli

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10
Q

What bacteria should colitis make you think of?

A

Shigella
Salmonella
Campylobacter jejuni
C diff

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11
Q

What bacteria should endocarditis make you think of?

A
Strep viridans (subacute)
Enterococcus (subacute)
Staph aureus (acute; IV drug users)
Strep pnuemo 

Coag neg staph (prosthetic valves)

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12
Q

What bacteria should meningitis make you think of?

A

Strep pneumo
N. meningitis
Listeria
H influenzae

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13
Q

Intraabdominal infections should make you think of which bacteria?

A

E coli
Klebsiella
Anaerobes (B. fragilis)
Enterococcus

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14
Q

Bacterial causes of STDs

A

N gonorrhea
Chlamydia trachomatis
Treponema pallidum
H. ducreyi

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15
Q

HSV (What’s the pathogen, is it painful, are lymph nodes involved, does it cause single or multiple lesions, and what’s the treatment)?

A

HSV 1 and 2

Yes, painful

Yes LNs involved

Multiple lesions

Treat with valacyclovir

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16
Q

Syphilis (What’s the pathogen, is it painful, are lymph nodes involved, does it cause single or multiple lesions, and what’s the treatment)?

A

Treponemia pallidum

No, primary lesion is NOT painful

Yes, non-tender

Single primary chancre

Penicilin

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17
Q

Chancroid (What’s the pathogen, is it painful, are lymph nodes involved, does it cause single or multiple lesions, and what’s the treatment)?

A

H. ducreyi (“School of fish” on Gram-stain)

Painful

Draining buboes

Multiple (undetermined red borders)

Azithromycin/ ceftriaxone

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18
Q

LGV (What’s the pathogen, is it painful, are lymph nodes involved, does it cause single or multiple lesions, and what’s the treatment)?

A

Chlamydia trachomatis L1-L3 serotypes

No

Draining, tender, “groove sign”

Single

Doxycycline for 3 weeks

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19
Q

Granuloma inguinale (Donovanosis)

(What’s the pathogen, is it painful, are lymph nodes involved, does it cause single or multiple lesions, and what’s the treatment)?

A

Klebsiella granulomatis

Not painful

No LN

Single beefy red lesion

Doxy for 3 weeks

20
Q

What’s the inflammatory component to the outer membrane in Gram-negative organisms?

A

LPS (lipopolysaccharide)

21
Q

Are techoic acids seen in Gram-positive or negative organisms or both?

A

Gram Postitive

22
Q

Non-Gram staining bugs?

A
Campylobacter (sometimes)
Mycoplasma 
Chlamydia 
Rickettsia
Spirochetes
Legionella
23
Q

Do we treat people who are colonized without symptoms?

A

NO!

Exceptions: TB, N. meningitis, syphilis, etc…

24
Q

Signs and symptoms of endocarditis

A
Fever
Roth spots 
Splinter hemorrhages
Kidney/hematuria
Joints
Stroke
Valve failure
25
What are the bugs that cause UTI in young women most commonly?
E coli | Staph saphrophyticus
26
What are the bugs that cause UTI in elderly men most commonly?
E coli | Enterococcus
27
What are the bugs that cause complicated UTIs?
GNRs (E coli, pseudomonas aeruginosa) Enterococcus (if catheter) Staph aureus
28
What is the most common cause of inflammatory diarrhea?
Campylobacter
29
Where in the body does inflammatory vs non-inflammatory diarrhea occur?
Inflammatory: colon Non-inflammatory: small intestine
30
What are the common pathogens that cause inflammatory diarrhea?
``` Campylobacter Shigella Salmonella +/- EHEC (doesn't cause fever or WBC) C diff ```
31
What are the common pathogens that cause non-inflammatory diarrhea?
``` Norwalk Rotavirus Astrovirus Cholera ETEC ```
32
Causes of bloody diarrhea
EHEC Ameobae Shiga 1 C diff
33
H-antigen | O-antigen
O- LPS | H- flagellum
34
Cholera toxin
Stimulates adenylyl cyclase
35
EPEC
attaches and effaces microvilli causing malabsorption
36
Complications from EHEC infection
HUS Thrombotic thrombocytopenic purpura (TTP)
37
In general, what antibiotic are most Strep sensitive to?
PCN ampicillin cephalosporins
38
What do we use to treat MSSA?
b-lactamase-resistant drug | 1° ceph, oxa/nafcillin, amp-sulbactam
39
What do we use to treat MRSA?
(IV) Vanco, daptomycin, linezolid
40
How do we treat coag neg staph?
Vanc | Dapto
41
What are the non-treponemal tests for syphilis?
PRP-VDLR
42
What are the treponemal tests for syphilis?
FTA-ABS TP-PA (less) Confirmatory
43
Norovirus
``` Family and community epidemics Older children, adults Shellfish Fecal-oral 1-2 duration ```
44
Rotavirus
``` Sporadic cases Infants, young children Fecal-oral 5-8 days duration Most common hospitalization, and deaths from diarrhea in children ```
45
Vaccine Preventable Diseases that we've learned about so far
Varicella (for primary) - children Zoster (for reactivation) - adults Papillomavirus – under age 26 (2-9 valent) Rotavirus (monovalent; 5-valent) Salmonella typhi (oral or parenteral) Typhoid vaccine