III. Autonomic Nervous System (receptors and actions) Flashcards Preview

Physiology > III. Autonomic Nervous System (receptors and actions) > Flashcards

Flashcards in III. Autonomic Nervous System (receptors and actions) Deck (35)
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1
Q

alpha-1 adrenoreceptor: mechanism of action

A

Increase IP3, increase intracellular Ca2+

2
Q

alpha-2 adrenoreceptor: mechanism of action

A

Inhibition of adenylyl cylase, decreased cAMP

3
Q

beta-1 adrenoreceptor: mechanism of action

A

Stimulation of adenylyl cylcase, increased cAMP

4
Q

beta-2 adrenoreceptor: mechanism of action

A

Stimulation of adenylyl cylcase, increased cAMP

5
Q

nicotinic cholinoreceptor: mechanism of action

A

Opening of Na+ and K+ channels; depolarization

6
Q

muscarinic cholinoreceptor (M1, M3, M5) : mechanism of action

A

increase IP3 and intracellular Ca2+

7
Q

muscarinic cholinoreceptor (M2, M4) : mechanism of action

A

decrease adenylyl cyclase

8
Q

Miosis (pupillary constriction)

A

Parasympathetic (M); via circular muscle of the iris

9
Q

Mydriasis (pupillary dilatation)

A

Sympathetic (alpha-1); via radial muscle of the iris

10
Q

Accomodation (near vision)

A

Parasympathetic (M); via ciliary muscle of the iris

11
Q

Ciliary muscle dilatation (far vision)

A

Sympathetic (beta)

12
Q

Increased cardiac muscle contractility; SA node (heart rate) and AV node (conduction) activityl;

A

Sympathetic (beta-1)

13
Q

Constriction of splanchnic vascular smooth muscle in skin

A

Sympathetic (alpha-1)

14
Q

Constriction of vascular smooth muscle in skeletal muscles

A

Sympathetic (beta-2)

15
Q

Bronchodilation

A

Sympathetic (beta-2)

16
Q

Bronchoconstriction

A

Parasympathetic (M)

17
Q

Relaxation of smooth muscle in the walls of the GI tract

A

Sympathetic (alpha-2, beta-2)

18
Q

Relaxation of smooth muscle in sphincters GI tract

A

Parasympathetic (M)

19
Q

Contraction of smooth muscle in the walls of the GI tract

A

Parasympathetic (M)

20
Q

Contraction of smooth muscle in the sphincters of the GI tract

A

Sympathetic (alpha-1)

21
Q

Increased mucoid saliva secretion

A

Sympathetic (beta-1)

22
Q

Increased serous saliva secretion

A

Parasympathetic (M)

23
Q

Increased gastric acid and pancreatic secretion

A

Parasympathetic (M)

24
Q

Bladder wall and detrusor muscle relaxation

A

Sympathetic (beta-2)

25
Q

Bladder wall and detrusor muscle contraction

A

Parasympathetic (M)

26
Q

Internal urethral sphincter tonic contraction

A

Sympathetic (alpha-1)

27
Q

Internal urethral sphincter relaxation

A

Parasympathetic (M)

28
Q

Ejaculation

A

Sympathetic (alpha)

29
Q

Penile erection

A

Parasympathetic (M)

30
Q

Increased sweating for thermoregulation

A

Sympathetic (M)

31
Q

Increased sweating due to stress

A

Sympathetic (alpha)

32
Q

Increased lacrimal gland secretion

A

Parasympathetic (M)

33
Q

Increased lipolysis in adipose tissue

A

Sympathetic (beta-3)

34
Q

Increased renin secretion

A

Sympathetic (beta-1)

35
Q

Decreased SA node (heart rate) and AV node (conduction) activity; decreased contractility in atria only

A

Parasympathetic (M)