Flashcards in ILD Deck (17)
What are examples of ILD associated with CT disease?
Systemic sclerosis, RA, dermatomyositis/polymyositis
What is systemic sclerosis?
MC CT disease associated with ILD; 50% to have diffuse pathology, 30% have limited involvement
What is the relationship between ILD and rheumatoid arthritis?
RA-ILD more common in males than females (in general RA affects F>M)
What is the relationship between ILD and dermatomyositis/polymyositis?
ILD associated with 45% of cases + anti-synthetase Abs; anti-synthetase syndrome (myositis, fever, Raynaud's, mechanic hands, arthritis, and ILD)
What are examples of pneumoconiosis?
Silicosis, asbestosis, coal worker disease, berylliosis
What is silicosis?
Associated with miners, stone cutters, sand blasting and quarry workers; long exposure can result in simple silicosis (radiographs show nodular lung disease and calcified hilar LNs)
What is complicated silicosis?
Progressive disease; radiographs show large nodules (>1cm) with extensive fibrosis
Pts with silicosis have increased risk of what?
infection especially Tb
What is asbestosis?
Associated with construction workers, insulation, demolition, and automobile workers; radiographs show multiple nodular opacities, pleural effusions, pleural fibrosis, may see blurring of diaphragm/cardiac silhouette
What is asbestos?
Fibrous material made of a composite of inorganic minerals
What are pts with asbestosis at increased risk for?
Increased risk of malignant mesothelioma and lung cancer (asbestosis and cigarette smoking has a synergistic effect on lung cancer rates)
What is coal workers pneumoconiosis (CWP)?
Inhalation of coal dust which has high levels of silica; affects miners
What is simple CWP?
Asymptomatic; radiology shows small nodules (<1cm) found most often at the apex
What is complicated CWP?
Symptomatic (cough, dyspnea, sputum production); PFTs show restrictive pattern; radiology shows large nodules (>1cm), patchy infiltrates at the bases and fibrosis
What is berylliosis?
Exposure to beryllium due to an occupation in manufacturing of alloys and electronic devices; increased risk of lung cancer; tx = steroids and removal of beryllium environment
What is acute berylliosis?
Rare, similar reaction to hypersensitivity pneumonitis, thought to be an immunologic response