Immune Response Flashcards
(25 cards)
1st line of defense
Innate response
types of cells in the adaptive response
T cells and B cells
types of T cells
- Helper T cells
- Cytotoxic T cells
- Memory T cells
Types of B cells
- Naive B cells
- Activated B cells
- Plasma B cells
- Memory B cells
Types of cells in native response
- Basophils
- Neutrophils
- Macrophage
- MAST Cells
- Natural Killer (NK) cells
Chemical mediators in Innate response
Cytokines- Interleukins/ histamines/ heparin
Chemical mediators in adaptive response
Cytokine/ antibodies
action time of native response
0-24 Hours (quick)
action time of adaptive response
days- weeks (slower)
Which immune response has specificity?
Adaptive response
Which response has memory?
Adaptive response
Which response has the highest potency?
Adaptive response
4 signs of infection
- Increased temp
- redness
- swelling
- pain
Stages of catching neutrophils on the endothelial cells
1) recruitment
2) captured
3) rolling
4) arrest
5) diapedesis/ extravasation
MAST Cell function
Release histamine and heparin which causes increased blood flow and permeability
neutrophils
first responder of the immune system, produce antimicrobial substances and enzymes to kill microbes
Reactive oxygen species function
signaling molecules that induce endocytosis, netosis, and secretes interleukins (IL-1b and IL-1a)
Macrophage function
engulfs and digests pathogens
Major Histocompatibility Complex II function
Protein that initiates immune responses
IgG binds to
antigens
IgD binds to
basophils and MAST cells
IgE binds to
B-cells
IgA binds
in mucous
IgM is secreted
First
