Immune response & recognition Flashcards
How does a dendritic cell activate a T-helper cell but not a T-cytotoxic cell?
Dendritic cell presents an antigen with MHC II, when presented with MHC II, only T-helper cells are activated.
T-cytotoxic cells need antigens to be presented with MHC I to become activated.
What does an antibody do?
An antibody binds to a pathogen blocking it’s ability to infect a host cell/neutralizes its function.
How do immune cells move around the body during an infection?
They congregate in the lymph node for activation, then travel throughout the body via the bloodstream.
What happens after an infection is cleared?
Contraction, most adaptive immune cells die when not needed. Some are kept as memory cells ready to be activated quickly if the same pathogen is recognised in the body again.
What cells have immune memory & how does it work?
Memory B cells originate from activated B cells after an infection/vaccination. They are stored long-term and rapidly produce antibodies upon re-exposure to the same pathogen.
